Rapid FTIR chemical imaging: highlighting FPA detectors

Konrad M. Dorling; Matthew J. Baker

doi:10.1016/j.tibtech.2013.05.008

Rapid FTIR chemical imaging: highlighting FPA detectors

Konrad M. Dorling^*, Matthew J. Baker

^*Corresponding author for this work

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

Fourier transform infrared (FTIR) spectroscopy is an established analytical technique that measures molecular bond vibrations via infrared absorption. The technique traditionally obtains single spectra from a sample, averaging the absorption information over a pre-determined aperture size. However, this averaging of information can be detrimental to pure biochemical analysis. The coupling of focal plane array (FPA) detectors to conventional FTIR systems and recent technical advances in FPA technology have allowed the concurrent rapid collection of thousands of infrared spectra over large areas of a sample, which has been particularly useful in tissue analysis. This novel technique presents a strong case for its use as a potential tool to aid in the clinic for disease diagnosis and assessment.

Original language	English
Pages (from-to)	437-438
Number of pages	2
Journal	Trends in Biotechnology
Volume	31
Issue number	8
Early online date	20 Jun 2013
DOIs	https://doi.org/10.1016/j.tibtech.2013.05.008
Publication status	Published - 1 Aug 2013

Keywords

Fourier transform infrared (FTIR) spectroscopy
chemical imaging
focal plane array (FPA) detectors
focal plane array detectors

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10.1016/j.tibtech.2013.05.008

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abstract = "Fourier transform infrared (FTIR) spectroscopy is an established analytical technique that measures molecular bond vibrations via infrared absorption. The technique traditionally obtains single spectra from a sample, averaging the absorption information over a pre-determined aperture size. However, this averaging of information can be detrimental to pure biochemical analysis. The coupling of focal plane array (FPA) detectors to conventional FTIR systems and recent technical advances in FPA technology have allowed the concurrent rapid collection of thousands of infrared spectra over large areas of a sample, which has been particularly useful in tissue analysis. This novel technique presents a strong case for its use as a potential tool to aid in the clinic for disease diagnosis and assessment. ",

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Rapid FTIR chemical imaging: highlighting FPA detectors

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Keywords

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