Rapid FTIR chemical imaging: highlighting FPA detectors

Konrad M. Dorling, Matthew J. Baker

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Fourier transform infrared (FTIR) spectroscopy is an established analytical technique that measures molecular bond vibrations via infrared absorption. The technique traditionally obtains single spectra from a sample, averaging the absorption information over a pre-determined aperture size. However, this averaging of information can be detrimental to pure biochemical analysis. The coupling of focal plane array (FPA) detectors to conventional FTIR systems and recent technical advances in FPA technology have allowed the concurrent rapid collection of thousands of infrared spectra over large areas of a sample, which has been particularly useful in tissue analysis. This novel technique presents a strong case for its use as a potential tool to aid in the clinic for disease diagnosis and assessment.

Original languageEnglish
Pages (from-to)437-438
Number of pages2
JournalTrends in Biotechnology
Volume31
Issue number8
Early online date20 Jun 2013
DOIs
Publication statusPublished - 1 Aug 2013

Keywords

  • Fourier transform infrared (FTIR) spectroscopy
  • chemical imaging
  • focal plane array (FPA) detectors
  • focal plane array detectors

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