Quantitative ultrasound differentiates brain and brain tumour phantoms

Hannah Thomson, Shufan Yang, Thomas Stritch, Mitch Baldwin, Helen Mulvana, Sandy Cochran

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

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Abstract

The acoustic impedance and attenuation of chicken liver and gizzard muscle were measured over a frequency range of 1-10MHz. The results validated their use as ultrasound phantoms for brain and brain tumour respectively. These tissues were then used as an initial test of whether quantitative ultrasound (QUS) could differentiate between brain and brain tumour tissue-like materials. QUS is a technique which infers information about tissue microstructure, such as effective scatterer diameter (ESD) and acoustic concentration, through the backscattered power spectrum of insonated tissues. The ESD of the brain tumour phantom was significantly higher than that of the healthy brain phantom, (87.3 ± 8.6 μm vs 61.2 ± 5.8 μm). The distinction in scattering properties shows potential to use QUS in soft tissue cancer detection.

Original languageEnglish
Title of host publication2019 IEEE International Ultrasonics Symposium, IUS 2019
Place of PublicationPiscataway, N.J.
Pages2420-2423
Number of pages4
ISBN (Electronic)9781728145969
DOIs
Publication statusPublished - 9 Dec 2019
Event2019 IEEE International Ultrasonics Symposium: IEEE UFFC - SECC, Glasgow, United Kingdom
Duration: 6 Oct 20199 Oct 2019
https://attend.ieee.org/ius-2019/

Publication series

NameIEEE International Ultrasonics Symposium, IUS
Volume2019-October
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2019 IEEE International Ultrasonics Symposium
Abbreviated titleIUS 2019
CountryUnited Kingdom
CityGlasgow
Period6/10/199/10/19
Internet address

Keywords

  • finite element analysis
  • quantitative ultrasound
  • tissue characterisation
  • tissue phantoms

Cite this

Thomson, H., Yang, S., Stritch, T., Baldwin, M., Mulvana, H., & Cochran, S. (2019). Quantitative ultrasound differentiates brain and brain tumour phantoms. In 2019 IEEE International Ultrasonics Symposium, IUS 2019 (pp. 2420-2423). (IEEE International Ultrasonics Symposium, IUS; Vol. 2019-October).. https://doi.org/10.1109/ULTSYM.2019.8925982