Quantitative ultrasound differentiates brain and brain tumour phantoms

Hannah Thomson; Shufan Yang; Thomas Stritch; Mitch Baldwin; Helen Mulvana; Sandy Cochran

doi:10.1109/ULTSYM.2019.8925982

Quantitative ultrasound differentiates brain and brain tumour phantoms

Hannah Thomson, Shufan Yang, Thomas Stritch, Mitch Baldwin, Helen Mulvana, Sandy Cochran

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution book

4 Citations (Scopus)

24 Downloads (Pure)

Abstract

The acoustic impedance and attenuation of chicken liver and gizzard muscle were measured over a frequency range of 1-10MHz. The results validated their use as ultrasound phantoms for brain and brain tumour respectively. These tissues were then used as an initial test of whether quantitative ultrasound (QUS) could differentiate between brain and brain tumour tissue-like materials. QUS is a technique which infers information about tissue microstructure, such as effective scatterer diameter (ESD) and acoustic concentration, through the backscattered power spectrum of insonated tissues. The ESD of the brain tumour phantom was significantly higher than that of the healthy brain phantom, (87.3 ± 8.6 μm vs 61.2 ± 5.8 μm). The distinction in scattering properties shows potential to use QUS in soft tissue cancer detection.

Original language	English
Title of host publication	2019 IEEE International Ultrasonics Symposium, IUS 2019
Place of Publication	Piscataway, N.J.
Pages	2420-2423
Number of pages	4
ISBN (Electronic)	9781728145969
DOIs	https://doi.org/10.1109/ULTSYM.2019.8925982
Publication status	Published - 9 Dec 2019
Event	2019 IEEE International Ultrasonics Symposium: IEEE UFFC - SECC, Glasgow, United Kingdom Duration: 6 Oct 2019 → 9 Oct 2019 https://attend.ieee.org/ius-2019/

Publication series

Name	IEEE International Ultrasonics Symposium, IUS
Volume	2019-October
ISSN (Print)	1948-5719
ISSN (Electronic)	1948-5727

Conference

Conference	2019 IEEE International Ultrasonics Symposium
Abbreviated title	IUS 2019
Country/Territory	United Kingdom
City	Glasgow
Period	6/10/19 → 9/10/19
Internet address	https://attend.ieee.org/ius-2019/

Funding

This work was supported by the UK Engineering and Physical Sciences Research Council (EPSRC) and Stryker Medical Devices under the project number.

Keywords

finite element analysis
quantitative ultrasound
tissue characterisation
tissue phantoms

Access to Document

10.1109/ULTSYM.2019.8925982

Thomson-etal-IEEE-IUS-2019-Quantitative-ultrasound-differentiates-brain-and-brainAccepted author manuscript, 848 KB

Cite this

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title = "Quantitative ultrasound differentiates brain and brain tumour phantoms",

abstract = "The acoustic impedance and attenuation of chicken liver and gizzard muscle were measured over a frequency range of 1-10MHz. The results validated their use as ultrasound phantoms for brain and brain tumour respectively. These tissues were then used as an initial test of whether quantitative ultrasound (QUS) could differentiate between brain and brain tumour tissue-like materials. QUS is a technique which infers information about tissue microstructure, such as effective scatterer diameter (ESD) and acoustic concentration, through the backscattered power spectrum of insonated tissues. The ESD of the brain tumour phantom was significantly higher than that of the healthy brain phantom, (87.3 ± 8.6 μm vs 61.2 ± 5.8 μm). The distinction in scattering properties shows potential to use QUS in soft tissue cancer detection.",

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author = "Hannah Thomson and Shufan Yang and Thomas Stritch and Mitch Baldwin and Helen Mulvana and Sandy Cochran",

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doi = "10.1109/ULTSYM.2019.8925982",

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Thomson, H, Yang, S, Stritch, T, Baldwin, M, Mulvana, H & Cochran, S 2019, Quantitative ultrasound differentiates brain and brain tumour phantoms. in 2019 IEEE International Ultrasonics Symposium, IUS 2019. IEEE International Ultrasonics Symposium, IUS, vol. 2019-October, Piscataway, N.J., pp. 2420-2423, 2019 IEEE International Ultrasonics Symposium, Glasgow, United Kingdom, 6/10/19. https://doi.org/10.1109/ULTSYM.2019.8925982

Quantitative ultrasound differentiates brain and brain tumour phantoms. / Thomson, Hannah; Yang, Shufan; Stritch, Thomas et al.
2019 IEEE International Ultrasonics Symposium, IUS 2019. Piscataway, N.J., 2019. p. 2420-2423 (IEEE International Ultrasonics Symposium, IUS; Vol. 2019-October).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution book

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N1 - © 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting /republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.

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Quantitative ultrasound differentiates brain and brain tumour phantoms

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