Quantitative simultaneous multianalyte detection of DNA by dual-wavelength surface-enhanced resonance raman scattering

K. Faulds, Fiona McKenzie, W.E. Smith, D. Graham

Research output: Contribution to journalArticle

125 Citations (Scopus)

Abstract

Dear SERRS: The quantitative detection of five labeled oligonucleotides by the title method (SERRS) without any separation is reported. The sensitivity of the multiplex analysis is the same as that for the individual dyes and indicates there is no compromise in the multiplexed format.
LanguageEnglish
Pages1829-1831
Number of pages2
JournalAgewandte Chemie-International Edition
Volume46
Issue number11
DOIs
Publication statusPublished - 2007

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Raman Spectrum Analysis
Oligonucleotides
Raman scattering
DNA
Coloring Agents
Dyes
Wavelength

Keywords

  • biosensors
  • DNA
  • multiplexing
  • Raman spectroscopy
  • surface-enhanced resonance raman scattering
  • SERRS
  • labeled DNA
  • silver
  • nanoparticles
  • fluorescence

Cite this

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KW - multiplexing

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KW - surface-enhanced resonance raman scattering

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KW - silver

KW - nanoparticles

KW - fluorescence

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