Quantitative simultaneous multianalyte detection of DNA by dual-wavelength surface-enhanced resonance raman scattering

K. Faulds, Fiona McKenzie, W.E. Smith, D. Graham

Research output: Contribution to journal › Article

127 Citations (Scopus)

Abstract

Dear SERRS: The quantitative detection of five labeled oligonucleotides by the title method (SERRS) without any separation is reported. The sensitivity of the multiplex analysis is the same as that for the individual dyes and indicates there is no compromise in the multiplexed format.
Original languageEnglish
Pages (from-to)1829-1831
Number of pages2
JournalAgewandte Chemie-International Edition
Volume46
Issue number11
DOIs
Publication statusPublished - 2007

Keywords

  • biosensors
  • DNA
  • multiplexing
  • Raman spectroscopy
  • surface-enhanced resonance raman scattering
  • SERRS
  • labeled DNA
  • silver
  • nanoparticles
  • fluorescence

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    • Projects

    NMS: EPSRC Science and Innovation Nanometrology for Molecular Science, Medicine and Manufacture

    Birch, D., Dawson, M., Faulds, K., Girkin, J., Graham, D., Martin, R., O'Donnell, K., Rolinski, O., Smith, W. & Wynne, K.

    Scottish Funding Council SFC, EPSRC (Engineering and Physical Sciences Research Council)

    1/08/08 → 31/01/12

    Project: Research

    Impacts

    Multiple target molecular diagnostics testing provides better diagnostics for healthcare

    Duncan Graham (Participant), W. Ewen Smith (Participant) & Karen Faulds (Participant)

    Impact: Impact - for External Portal › Economic and commerce, Health and welfare - new products, guidelines and services

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