Quantitative SERRS immunoassay for the detection of human PSA

Ross Stevenson; Andrew Martin Ingram; H. Leung; D. MacMillan; Duncan Graham

doi:10.1039/B902174D

Quantitative SERRS immunoassay for the detection of human PSA

Ross Stevenson, Andrew Martin Ingram, H. Leung, D. MacMillan, Duncan Graham

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

We report the first use of a commonly used ELISA colorimetric substrate as a SERRS marker and show how it can be used for the detection of pg ml−1 levels of human prostate specific antigen (PSA) in clinical samples. The technique is amenable over a wide range of concentrations and lends itself to future multiplexing analysis.

Original language	English
Pages (from-to)	842-844
Number of pages	3
Journal	Analyst
Volume	134
Issue number	5
Early online date	17 Mar 2009
DOIs	https://doi.org/10.1039/B902174D
Publication status	Published - 2009

Keywords

SERRS
human prostate specific antigen
multiplexing analysis

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10.1039/B902174D

OPTICAL SPECTROSCOPIES FOR IMMUNO-BIOMEDICAL APPLICATIONS
Graham, D. (Principal Investigator), Alexander, J. (Co-investigator), Birch, D. (Co-investigator), Faulds, K. (Co-investigator), Garside, P. (Co-investigator) & Smith, W. (Co-investigator)
EPSRC (Engineering and Physical Sciences Research Council)
1/08/06 → 31/01/12
Project: Research

Cite this

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title = "Quantitative SERRS immunoassay for the detection of human PSA",

abstract = "We report the first use of a commonly used ELISA colorimetric substrate as a SERRS marker and show how it can be used for the detection of pg ml−1 levels of human prostate specific antigen (PSA) in clinical samples. The technique is amenable over a wide range of concentrations and lends itself to future multiplexing analysis.",

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AB - We report the first use of a commonly used ELISA colorimetric substrate as a SERRS marker and show how it can be used for the detection of pg ml−1 levels of human prostate specific antigen (PSA) in clinical samples. The technique is amenable over a wide range of concentrations and lends itself to future multiplexing analysis.

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KW - human prostate specific antigen

KW - multiplexing analysis

U2 - 10.1039/B902174D

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Quantitative SERRS immunoassay for the detection of human PSA

Abstract

Keywords

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OPTICAL SPECTROSCOPIES FOR IMMUNO-BIOMEDICAL APPLICATIONS

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