Projects per year
Abstract
A novel method for quantifying biomolecules immobilised onto gold and silver nanoparticles is reported; fluorescent-labelled antibodies and DNA are hydrolysed on the surface of the nanoparticles by the addition of trypsin and DNase I, respectively, resulting in the release of the quantifiable fluorescent label into the bulk solution.
| Original language | English |
|---|---|
| Pages (from-to) | 2872-2874 |
| Number of pages | 2 |
| Journal | Chemical Communications (London) |
| Issue number | 20 |
| DOIs | |
| Publication status | Published - 31 Mar 2009 |
Keywords
- biomolecules
- gold nanoparticles
- silver nanoparticles
- immobilised biomolecules
- fluorescent-labelled antibodies
- DNA
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Dive into the research topics of 'Quantitation of biomolecules conjugated to nanoparticles by enzyme hydrolysis'. Together they form a unique fingerprint.Projects
- 1 Finished
-
NMS: EPSRC Science and Innovation Nanometrology for Molecular Science, Medicine and Manufacture
Birch, D. (Principal Investigator), Dawson, M. (Co-investigator), Faulds, K. (Co-investigator), Girkin, J. (Co-investigator), Graham, D. (Co-investigator), Martin, R. (Co-investigator), O'Donnell, K. (Co-investigator), Rolinski, O. (Co-investigator), Smith, W. (Co-investigator) & Wynne, K. (Co-investigator)
Scottish Funding Council SFC, EPSRC (Engineering and Physical Sciences Research Council)
1/08/08 → 31/01/12
Project: Research
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