Putting the squeeze on mephedrone hydrogen sulfate

Natsiri Satthaphut, Oliver B. Sutcliffe, Iain D. H. Oswald

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Herein we report the characterisation of a novel salt of the ``legal high'' (+/-)-4'-methylmethcathinone hydrogen sulfate and its polymorphism under ambient and high pressure conditions. Under ambient pressure only one polymorph of the title compound was isolated but when subjected to high pressure a further two polymorphs are observed. The phase transitions at >0.5 GPa and >3.6 GPa are reversible single crystal to single crystal transitions which is possible due to the similarity of the packing in the molecules. It is proposed that these transitions are driven by the pV term of the Gibbs Free Energy equation rather than by the relief of repulsive interactions between molecules.
LanguageEnglish
Pages101-111
Number of pages11
JournalZeitschrift fur Kristallografie
Volume229
Issue number2
Early online date5 Feb 2014
DOIs
Publication statusPublished - Mar 2014

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Polymorphism
Sulfates
Hydrogen
sulfates
Pressure
hydrogen
Single crystals
Molecules
Phase Transition
single crystals
polymorphism
Gibbs free energy
molecules
Salts
Phase transitions
salts
mephedrone
interactions

Keywords

  • high pressure
  • illicit materials
  • polymorphism
  • single-crystal transition

Cite this

Satthaphut, Natsiri ; Sutcliffe, Oliver B. ; Oswald, Iain D. H. / Putting the squeeze on mephedrone hydrogen sulfate. In: Zeitschrift fur Kristallografie. 2014 ; Vol. 229, No. 2. pp. 101-111.
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Putting the squeeze on mephedrone hydrogen sulfate. / Satthaphut, Natsiri; Sutcliffe, Oliver B.; Oswald, Iain D. H.

In: Zeitschrift fur Kristallografie, Vol. 229, No. 2, 03.2014, p. 101-111.

Research output: Contribution to journalArticle

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