Pulsed UV-light in activation of poliovirus and adenovirus

Y. Lamont, A. Rzeutka, J.G. Anderson, S.J. MacGregor, M.J. Given, C. Deppe, N. Cook

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Abstract

To study the pulsed ultraviolet (UV) inactivation of poliovirus and adenovirus.

Viral suspensions of 2 ml volume were exposed to varying numbers of polychromatic light pulses emitted from a xenon flashlamp. Ten pulses produced an approximately 4 log10 reduction in poliovirus titre, and no infectious poliovirus remained after 25 pulses. With adenovirus, 10 pulses resulted in an approximately 1 log10 reduction in infectivity. Adenovirus required 100 pulses to produce an approximately 3 log10 reduction in infectivity, and 200 pulses to produce a greater than 4 log10 reduction.

Adenovirus was more resistant to pulsed UV treatment than poliovirus although both viruses showed susceptibility to the treatment.

Pulsed UV-light treatment proved successful in the inactivation of poliovirus and adenovirus, and represents an alternative to continuous-wave UV treatment.
Original languageEnglish
Pages (from-to)564-567
Number of pages4
JournalLetters in Applied Microbiology
Volume45
Issue number5
DOIs
Publication statusPublished - Nov 2007

Keywords

  • adenovirus
  • poliovirus
  • pulsed
  • ultraviolet light
  • UV inactivation

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