Psychological effects of cognitive behaviour therapy (CBT) for persistent insomnia associated with cancer: randomised controlled trial (RCT)

C. A. Espie, L. M. Fleming, J. Cassidy, L. Samuel, J. Paul

Research output: Contribution to journalConference Contribution

147 Citations (Scopus)

Abstract

Introduction: Insomnia can be caused, or exacerbated, by the stress of having cancer, and up to 40% of patients report persistent sleep problems. Whereas CBT is effective for primary insomnia, the treatment literature on insomnia related to cancer is sparse. Moreover, little in known about psychological changes following CBT for insomnia in this population. Methods: Pragmatic, two-centre RCT of CBT versus treatment as usual (TAU). Patients meeting diagnostic criteria for persistent insomnia recruited after completion of active anti-cancer therapy for breast, prostate, colorectal or gynaecological cancer. Major assessments at baseline, post-treatment and 6-month follow-up. CBT comprised 5, weekly, 1-h, small group sessions led by a cancer nurse following a validated CBT manual. TAU comprised usual care. Outcomes measured using validated and reliable questionnaires/rating scales of dysfunctional thinking and attribution. Results: Data from 150 participants (103F; mean age 61 year) analysed on intention-to-treat basis. Significant reductions in subscales of the Dysfunctional Beliefs and Attitudes about Sleep scale (range of ES 5 0.65–1.04), and the Sleep Disturbance Questionnaire (range of ES 5 0.95–1.18), observed in CBT at post-treatment, relative to TAU. These ES increased to .95–1.33 for DBAS, and .82–1.37 for SDQ at follow up. Conclusion: Cognitive adjustment associated with successful CBT treatment for insomnia in cancer patients appears similar to that observed in primary insomnia, supporting the notion that insomnia associated with cancer may be treated similarly to the primary insomnia syndrome. Acknowledgement: Support This research was supported by Cancer Research UK and the Dr. Mortimer & Theresa Sackler Foundation.
LanguageEnglish
Pages34-34
Number of pages1
JournalJournal of Sleep Research
Volume17
Issue numbers1
DOIs
Publication statusPublished - 30 Dec 2008
Externally publishedYes
Event19th Congress of the European Sleep Research Society - Glasgow, United Kingdom
Duration: 9 Sep 200813 Sep 2008
Conference number: 19th

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Sleep Initiation and Maintenance Disorders
Cognitive Therapy
Randomized Controlled Trials
Psychology
Neoplasms
Sleep
Therapeutics
Social Adjustment
Research
Prostate
Nurses
Breast Neoplasms

Keywords

  • cognitive behaviour therapy
  • cancer
  • insomnia

Cite this

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title = "Psychological effects of cognitive behaviour therapy (CBT) for persistent insomnia associated with cancer: randomised controlled trial (RCT)",
abstract = "Introduction: Insomnia can be caused, or exacerbated, by the stress of having cancer, and up to 40{\%} of patients report persistent sleep problems. Whereas CBT is effective for primary insomnia, the treatment literature on insomnia related to cancer is sparse. Moreover, little in known about psychological changes following CBT for insomnia in this population. Methods: Pragmatic, two-centre RCT of CBT versus treatment as usual (TAU). Patients meeting diagnostic criteria for persistent insomnia recruited after completion of active anti-cancer therapy for breast, prostate, colorectal or gynaecological cancer. Major assessments at baseline, post-treatment and 6-month follow-up. CBT comprised 5, weekly, 1-h, small group sessions led by a cancer nurse following a validated CBT manual. TAU comprised usual care. Outcomes measured using validated and reliable questionnaires/rating scales of dysfunctional thinking and attribution. Results: Data from 150 participants (103F; mean age 61 year) analysed on intention-to-treat basis. Significant reductions in subscales of the Dysfunctional Beliefs and Attitudes about Sleep scale (range of ES 5 0.65–1.04), and the Sleep Disturbance Questionnaire (range of ES 5 0.95–1.18), observed in CBT at post-treatment, relative to TAU. These ES increased to .95–1.33 for DBAS, and .82–1.37 for SDQ at follow up. Conclusion: Cognitive adjustment associated with successful CBT treatment for insomnia in cancer patients appears similar to that observed in primary insomnia, supporting the notion that insomnia associated with cancer may be treated similarly to the primary insomnia syndrome. Acknowledgement: Support This research was supported by Cancer Research UK and the Dr. Mortimer & Theresa Sackler Foundation.",
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Psychological effects of cognitive behaviour therapy (CBT) for persistent insomnia associated with cancer : randomised controlled trial (RCT). / Espie, C. A.; Fleming, L. M.; Cassidy, J.; Samuel, L.; Paul, J.

In: Journal of Sleep Research, Vol. 17, No. s1, 30.12.2008, p. 34-34.

Research output: Contribution to journalConference Contribution

TY - JOUR

T1 - Psychological effects of cognitive behaviour therapy (CBT) for persistent insomnia associated with cancer

T2 - Journal of Sleep Research

AU - Espie, C. A.

AU - Fleming, L. M.

AU - Cassidy, J.

AU - Samuel, L.

AU - Paul, J.

PY - 2008/12/30

Y1 - 2008/12/30

N2 - Introduction: Insomnia can be caused, or exacerbated, by the stress of having cancer, and up to 40% of patients report persistent sleep problems. Whereas CBT is effective for primary insomnia, the treatment literature on insomnia related to cancer is sparse. Moreover, little in known about psychological changes following CBT for insomnia in this population. Methods: Pragmatic, two-centre RCT of CBT versus treatment as usual (TAU). Patients meeting diagnostic criteria for persistent insomnia recruited after completion of active anti-cancer therapy for breast, prostate, colorectal or gynaecological cancer. Major assessments at baseline, post-treatment and 6-month follow-up. CBT comprised 5, weekly, 1-h, small group sessions led by a cancer nurse following a validated CBT manual. TAU comprised usual care. Outcomes measured using validated and reliable questionnaires/rating scales of dysfunctional thinking and attribution. Results: Data from 150 participants (103F; mean age 61 year) analysed on intention-to-treat basis. Significant reductions in subscales of the Dysfunctional Beliefs and Attitudes about Sleep scale (range of ES 5 0.65–1.04), and the Sleep Disturbance Questionnaire (range of ES 5 0.95–1.18), observed in CBT at post-treatment, relative to TAU. These ES increased to .95–1.33 for DBAS, and .82–1.37 for SDQ at follow up. Conclusion: Cognitive adjustment associated with successful CBT treatment for insomnia in cancer patients appears similar to that observed in primary insomnia, supporting the notion that insomnia associated with cancer may be treated similarly to the primary insomnia syndrome. Acknowledgement: Support This research was supported by Cancer Research UK and the Dr. Mortimer & Theresa Sackler Foundation.

AB - Introduction: Insomnia can be caused, or exacerbated, by the stress of having cancer, and up to 40% of patients report persistent sleep problems. Whereas CBT is effective for primary insomnia, the treatment literature on insomnia related to cancer is sparse. Moreover, little in known about psychological changes following CBT for insomnia in this population. Methods: Pragmatic, two-centre RCT of CBT versus treatment as usual (TAU). Patients meeting diagnostic criteria for persistent insomnia recruited after completion of active anti-cancer therapy for breast, prostate, colorectal or gynaecological cancer. Major assessments at baseline, post-treatment and 6-month follow-up. CBT comprised 5, weekly, 1-h, small group sessions led by a cancer nurse following a validated CBT manual. TAU comprised usual care. Outcomes measured using validated and reliable questionnaires/rating scales of dysfunctional thinking and attribution. Results: Data from 150 participants (103F; mean age 61 year) analysed on intention-to-treat basis. Significant reductions in subscales of the Dysfunctional Beliefs and Attitudes about Sleep scale (range of ES 5 0.65–1.04), and the Sleep Disturbance Questionnaire (range of ES 5 0.95–1.18), observed in CBT at post-treatment, relative to TAU. These ES increased to .95–1.33 for DBAS, and .82–1.37 for SDQ at follow up. Conclusion: Cognitive adjustment associated with successful CBT treatment for insomnia in cancer patients appears similar to that observed in primary insomnia, supporting the notion that insomnia associated with cancer may be treated similarly to the primary insomnia syndrome. Acknowledgement: Support This research was supported by Cancer Research UK and the Dr. Mortimer & Theresa Sackler Foundation.

KW - cognitive behaviour therapy

KW - cancer

KW - insomnia

UR - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2869

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DO - 10.1111/j.1365-2869.2008.00690.x

M3 - Conference Contribution

VL - 17

SP - 34

EP - 34

JO - Journal of Sleep Research

JF - Journal of Sleep Research

SN - 0962-1105

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