Protein folding in hydrophobic-polar lattice model: a flexible ant-colony optimization approach

Xiao Min Hu, Jun Zhang, Jing Xiao, Yun Li

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

This paper proposes a flexible ant colony (FAC) algorithm for solving protein folding problems based on the hydrophobic-polar square lattice model. Collaborations of novel pheromone and heuristic strategies in the proposed algorithm make it more effective in predicting structures of proteins compared with other state-of-the-art algorithms.

Original languageEnglish
Pages (from-to)469-477
Number of pages9
JournalProtein and Peptide Letters
Volume15
Issue number5
DOIs
Publication statusPublished - 1 Jun 2008

Keywords

  • ant colony optimization
  • hydrophobic-polar (HP) model
  • protein folding
  • protein structure prediction

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