Prognostic significance of being overweight and obese at diagnosis in children with acute lymphoblastic leukemia

F.K. Aldhafiri, J.H. McColl, J.J. Reilly

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

This study tested the hypothesis that being overweight/obese at diagnosis of childhood ALL was related to risk of relapse. In a national cohort of 1033 patients from the UK, there was no evidence that weight status at diagnosis was related significantly to risk of relapse: log-rank test (P=0.90) with overweight and obesity as the exposure (n=917); individual (P=0.42) and stepwise (P=0.96) proportional hazards models, with BMI Z score as the exposure. The study does not support the hypothesis that being overweight/obese at diagnosis impairs prognosis in childhood ALL in the UK.
Original languageEnglish
Pages (from-to)234-236
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Volume36
Issue number3
DOIs
Publication statusPublished - 1 Jan 2014

Keywords

  • acute lymphoblastic leukemia
  • overwieght children
  • obese children

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