Prognostic significance of being overweight and obese at diagnosis in children with acute lymphoblastic leukemia

F.K. Aldhafiri; J.H. McColl; J.J. Reilly

doi:10.1097/MPH.0000000000000056

Prognostic significance of being overweight and obese at diagnosis in children with acute lymphoblastic leukemia

F.K. Aldhafiri, J.H. McColl, J.J. Reilly

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

This study tested the hypothesis that being overweight/obese at diagnosis of childhood ALL was related to risk of relapse. In a national cohort of 1033 patients from the UK, there was no evidence that weight status at diagnosis was related significantly to risk of relapse: log-rank test (P=0.90) with overweight and obesity as the exposure (n=917); individual (P=0.42) and stepwise (P=0.96) proportional hazards models, with BMI Z score as the exposure. The study does not support the hypothesis that being overweight/obese at diagnosis impairs prognosis in childhood ALL in the UK.

Original language	English
Pages (from-to)	234-236
Number of pages	3
Journal	Journal of Pediatric Hematology/Oncology
Volume	36
Issue number	3
DOIs	https://doi.org/10.1097/MPH.0000000000000056
Publication status	Published - 1 Jan 2014

Keywords

acute lymphoblastic leukemia
overwieght children
obese children

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/MPH.0000000000000056

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abstract = "This study tested the hypothesis that being overweight/obese at diagnosis of childhood ALL was related to risk of relapse. In a national cohort of 1033 patients from the UK, there was no evidence that weight status at diagnosis was related significantly to risk of relapse: log-rank test (P=0.90) with overweight and obesity as the exposure (n=917); individual (P=0.42) and stepwise (P=0.96) proportional hazards models, with BMI Z score as the exposure. The study does not support the hypothesis that being overweight/obese at diagnosis impairs prognosis in childhood ALL in the UK.",

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N2 - This study tested the hypothesis that being overweight/obese at diagnosis of childhood ALL was related to risk of relapse. In a national cohort of 1033 patients from the UK, there was no evidence that weight status at diagnosis was related significantly to risk of relapse: log-rank test (P=0.90) with overweight and obesity as the exposure (n=917); individual (P=0.42) and stepwise (P=0.96) proportional hazards models, with BMI Z score as the exposure. The study does not support the hypothesis that being overweight/obese at diagnosis impairs prognosis in childhood ALL in the UK.

AB - This study tested the hypothesis that being overweight/obese at diagnosis of childhood ALL was related to risk of relapse. In a national cohort of 1033 patients from the UK, there was no evidence that weight status at diagnosis was related significantly to risk of relapse: log-rank test (P=0.90) with overweight and obesity as the exposure (n=917); individual (P=0.42) and stepwise (P=0.96) proportional hazards models, with BMI Z score as the exposure. The study does not support the hypothesis that being overweight/obese at diagnosis impairs prognosis in childhood ALL in the UK.

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Prognostic significance of being overweight and obese at diagnosis in children with acute lymphoblastic leukemia

Abstract

Keywords

UN SDGs

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