Abstract
Preliminary data for production of ℓ-malic acid from calcium acetate by Paecilomyces varioti is presented. Shake flask cultures with free cells and with cells immobilised in calcium alginate beads gave comparable results, acid concentrations of approximately 8 g/l being produced after 5 days from a medium containing 4% w/w of calcium acetate. A packed bed reactor, operated as an extended batch with product recycle, produced maximum acid concentrations of 32.6 g/l, equivalent to 73% of the maximum theoretical yield, after 3 days. Evidence obtained indicated that spores were more active than mycelia in the production of malic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 393-398 |
| Number of pages | 6 |
| Journal | Biotechnology Letters |
| Volume | 9 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 1987 |
Keywords
- ℓ-malic acid
- calcium acetate
- Paecilomyces varioti
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