Prevalence of depression among Iranian patients with rheumatoid arthritis: a systematic review and meta-analysis

Tayebeh Jamshidi, Reza Ghanei Gheshlagh, Fariba Ebtekar, Sahar Dalvand, Amir Vahedian Azimi, Amanj Kurdi

Research output: Contribution to journalArticle

Abstract

Patients with rheumatoid arthritis (RA) are prone to depression due to several factors related to their RA, including chronic and persistent pain, functional disability, economic constraints, and the side effects of RA medication. Previous Iranian studies showed conflicting and inconclusive findings regarding the prevalence of depression among RA patients. Therefore, this systematic review and meta-analysis was conducted to estimate the true prevalence of depression in Iranian patients with RA. Search for eligible articles was performed using the keywords of depression, depressive disorder, dysthymic disorder, major depressive disorder, RA, and Iran, and their possible combinations in the following databases: Scientific Information Database, MagIran, Web of Science/ISI, PubMed, and Scopus. The search was restricted to articles published in Persian and English languages. The meta-analysis was performed using the random effects model, and the data were analyzed using the STATA software version 12. Overall, six articles were selected; the overall prevalence of depression among the Iranian patients with RA was 65.58% (95% CI: 56.53%-74.62%). There were no significant relationships between the prevalence of depression and articles' methodological quality and year of publication, participants' age, sample size, and duration of disease. More than half of RA patients suffer from depression. The overlap between the physical symptoms of RA and depression in this group of patients makes it difficult to correctly diagnose depression; therefore, initiative and efforts are required to improve the identification of early depression symptoms in RA patients in order to effectively manage their depression.

LanguageEnglish
Pages53-59
Number of pages7
JournalOpen Access Rheumatology: Research and Reviews
Volume2019
Issue number11
DOIs
Publication statusPublished - 13 Feb 2019

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Meta-Analysis
Rheumatoid Arthritis
Depression
Dysthymic Disorder
Databases
Major Depressive Disorder
Depressive Disorder
Iran
PubMed
Chronic Pain
Sample Size
Publications
Language
Software
Economics

Keywords

  • rheumatoid arthritis
  • depression
  • Iran
  • meta-analysis
  • prevalence

Cite this

Jamshidi, Tayebeh ; Gheshlagh, Reza Ghanei ; Ebtekar, Fariba ; Dalvand, Sahar ; Azimi, Amir Vahedian ; Kurdi, Amanj. / Prevalence of depression among Iranian patients with rheumatoid arthritis : a systematic review and meta-analysis. In: Open Access Rheumatology: Research and Reviews. 2019 ; Vol. 2019, No. 11. pp. 53-59.
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Prevalence of depression among Iranian patients with rheumatoid arthritis : a systematic review and meta-analysis. / Jamshidi, Tayebeh ; Gheshlagh, Reza Ghanei; Ebtekar, Fariba; Dalvand, Sahar; Azimi, Amir Vahedian; Kurdi, Amanj.

In: Open Access Rheumatology: Research and Reviews, Vol. 2019, No. 11, 13.02.2019, p. 53-59.

Research output: Contribution to journalArticle

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