Abstract
| Language | English |
|---|---|
| Pages | 76–79 |
| Number of pages | 4 |
| Journal | Journal of Human Nutrition and Dietetics |
| Volume | 27 |
| Issue number | 1 |
| Early online date | 20 Jun 2013 |
| DOIs | |
| Publication status | Published - Feb 2014 |
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Keywords
- underweight
- overweight
- obesity
- patients
- ALL
- acute lymphoblastic leukaemia
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Prevalence of being underweight and overweight and obesity at diagnosis in UK patients with childhood acute lymphoblastic leukaemia 1985–2002. / Aldhafiri, F. K. ; McColl, John H.; Reilly, John.
In: Journal of Human Nutrition and Dietetics, Vol. 27, No. 1, 02.2014, p. 76–79.Research output: Contribution to journal › Article
TY - JOUR
T1 - Prevalence of being underweight and overweight and obesity at diagnosis in UK patients with childhood acute lymphoblastic leukaemia 1985–2002
AU - Aldhafiri, F. K.
AU - McColl, John H.
AU - Reilly, John
PY - 2014/2
Y1 - 2014/2
N2 - Being underweight or overweight and obesity at diagnosis may all worsen prognosis in childhood acute lymphoblastic leukaemia (ALL), although no studies have estimated the prevalence of an unhealthy weight status at diagnosis in large representative samples using contemporary definitions of weight status based on body mass index (BMI) for age. The present study comprised a retrospective study that aimed to estimate prevalence of being underweight and overweight and obesity at diagnosis for patients with childhood ALL on three successive UK treatment trials: UKALL X (1985–1990; n = 1033), UKALL XI (1990–1997; n = 2031), UKALL 97/99 (1997–2002; n = 898).The BMI for age was used to define weight status with both UK 1990 BMI for age reference data and the Cole-International Obesity Task Force (IOTF) definitions. The prevalence of being underweight was 6% in the most recent trial for which data were available. The prevalence of being overweight and obesity was 35% in the most recent trial when expressed using Cole-IOTF definitions and 41% when expressed relative to UK 1990 reference data. Even with highly conservative estimates, >40% of all UK patients with ALL were underweight, overweight or obese at diagnosis in the most recent trial for which UK data are available (UKALL 97/99, 1997–2002).
AB - Being underweight or overweight and obesity at diagnosis may all worsen prognosis in childhood acute lymphoblastic leukaemia (ALL), although no studies have estimated the prevalence of an unhealthy weight status at diagnosis in large representative samples using contemporary definitions of weight status based on body mass index (BMI) for age. The present study comprised a retrospective study that aimed to estimate prevalence of being underweight and overweight and obesity at diagnosis for patients with childhood ALL on three successive UK treatment trials: UKALL X (1985–1990; n = 1033), UKALL XI (1990–1997; n = 2031), UKALL 97/99 (1997–2002; n = 898).The BMI for age was used to define weight status with both UK 1990 BMI for age reference data and the Cole-International Obesity Task Force (IOTF) definitions. The prevalence of being underweight was 6% in the most recent trial for which data were available. The prevalence of being overweight and obesity was 35% in the most recent trial when expressed using Cole-IOTF definitions and 41% when expressed relative to UK 1990 reference data. Even with highly conservative estimates, >40% of all UK patients with ALL were underweight, overweight or obese at diagnosis in the most recent trial for which UK data are available (UKALL 97/99, 1997–2002).
KW - underweight
KW - overweight
KW - obesity
KW - patients
KW - ALL
KW - acute lymphoblastic leukaemia
UR - http://www.scopus.com/inward/record.url?scp=84879113877&partnerID=8YFLogxK
UR - http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291365-277X
U2 - 10.1111/jhn.12112
DO - 10.1111/jhn.12112
M3 - Article
VL - 27
SP - 76
EP - 79
JO - Journal of Human Nutrition and Dietetics
T2 - Journal of Human Nutrition and Dietetics
JF - Journal of Human Nutrition and Dietetics
SN - 0952-3871
IS - 1
ER -