Plasma potassium concentration was measured at admission in 1234 patients who presented with acute chest pain. One hundred and ninety five patients were on P blockers before admission. The potassium concentrations of patients admitted early (within four hours of onsetof symptoms) were compared with those admitted later (4-18 hours after onset of symptoms). There was a transient fall in plasma potassium concentrations in patients not pre-treated with , B blockers. This was not seen in patients who had been on P blockers before admission. Nonselective, B blockers were more effective than cardioselective agents in maintaining concentrationsof plasma potassium. These findings suggest a mechanism for the beneficial effects of ,B blockers on morbidity and mortality in acute myocardial infarction.
- acute chest pain
Simpson, E., Rodger, J. C., Raj, S. M., Wong, C., Wilkie, L., & Robertson, C. (1987). Pretreatment with beta-blockers and the frequency of hypokalemia in patients with acute chest pain. British Heart Journal, 58(5), 499-504. https://doi.org/10.1136/hrt.58.5.499