Pretreatment with beta-blockers and the frequency of hypokalemia in patients with acute chest pain

Elliott Simpson, J. Christine Rodger, S. Mahendra Raj, Chris Wong, Laura Wilkie, Christopher Robertson

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Plasma potassium concentration was measured at admission in 1234 patients who presented with acute chest pain. One hundred and ninety five patients were on P blockers before admission. The potassium concentrations of patients admitted early (within four hours of onsetof symptoms) were compared with those admitted later (4-18 hours after onset of symptoms). There was a transient fall in plasma potassium concentrations in patients not pre-treated with , B blockers. This was not seen in patients who had been on P blockers before admission. Nonselective, B blockers were more effective than cardioselective agents in maintaining concentrationsof plasma potassium. These findings suggest a mechanism for the beneficial effects of ,B blockers on morbidity and mortality in acute myocardial infarction.
LanguageEnglish
Pages499-504
Number of pages6
JournalBritish Heart Journal
Volume58
Issue number5
DOIs
Publication statusPublished - Nov 1987

Fingerprint

Hypokalemia
Acute Pain
Chest Pain
Potassium
Myocardial Infarction
Morbidity
Mortality

Keywords

  • beta-blockers
  • hypokalemia
  • acute chest pain

Cite this

Simpson, Elliott ; Rodger, J. Christine ; Raj, S. Mahendra ; Wong, Chris ; Wilkie, Laura ; Robertson, Christopher. / Pretreatment with beta-blockers and the frequency of hypokalemia in patients with acute chest pain. In: British Heart Journal. 1987 ; Vol. 58, No. 5. pp. 499-504.
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Pretreatment with beta-blockers and the frequency of hypokalemia in patients with acute chest pain. / Simpson, Elliott; Rodger, J. Christine; Raj, S. Mahendra; Wong, Chris; Wilkie, Laura; Robertson, Christopher.

In: British Heart Journal, Vol. 58, No. 5, 11.1987, p. 499-504.

Research output: Contribution to journalArticle

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AU - Simpson, Elliott

AU - Rodger, J. Christine

AU - Raj, S. Mahendra

AU - Wong, Chris

AU - Wilkie, Laura

AU - Robertson, Christopher

PY - 1987/11

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N2 - Plasma potassium concentration was measured at admission in 1234 patients who presented with acute chest pain. One hundred and ninety five patients were on P blockers before admission. The potassium concentrations of patients admitted early (within four hours of onsetof symptoms) were compared with those admitted later (4-18 hours after onset of symptoms). There was a transient fall in plasma potassium concentrations in patients not pre-treated with , B blockers. This was not seen in patients who had been on P blockers before admission. Nonselective, B blockers were more effective than cardioselective agents in maintaining concentrationsof plasma potassium. These findings suggest a mechanism for the beneficial effects of ,B blockers on morbidity and mortality in acute myocardial infarction.

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