Preparation of the MacMillan Imidazolidinones

Leopold Samulis; Nicholas C.O. Tomkinson

doi:10.1016/j.tet.2011.04.009

Preparation of the MacMillan Imidazolidinones

Leopold Samulis, Nicholas C.O. Tomkinson

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

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Abstract

A general method for the preparation of the MacMillan imidazolidinones is described. Treatment of an α-amino amide with a carbonyl compound in refluxing chloroform in the presence of Yb(OTf)3 (1 mol%) provides convenient access to the corresponding imidazolidinones

Original language	English
Pages (from-to)	4263-4267
Number of pages	5
Journal	Tetrahedron
Volume	67
Issue number	23
DOIs	https://doi.org/10.1016/j.tet.2011.04.009
Publication status	Published - 10 Jun 2011

Keywords

MacMillan imidazolidinones
carbonyl
chloroform
imidazolidinones

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10.1016/j.tet.2011.04.009

Prepartion of the MacMillan ImidazolidinonesAccepted author manuscript, 1.87 MB

30 Citations
1 Chapter

Organocatalysed transformations of alpha,beta-unsaturated carbonyl compoundsthrough iminium ion intermediates
Tomkinson, N. & Rowley, J., 14 Nov 2012, Asymmetric Synthesis : More Methods and Applications. Christmann, M. & Brase, S. (eds.). Weinheim, p. 29-34 6 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter

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title = "Preparation of the MacMillan Imidazolidinones",

abstract = "A general method for the preparation of the MacMillan imidazolidinones is described. Treatment of an α-amino amide with a carbonyl compound in refluxing chloroform in the presence of Yb(OTf)3 (1 mol%) provides convenient access to the corresponding imidazolidinones",

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author = "Leopold Samulis and Tomkinson, {Nicholas C.O.}",

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T1 - Preparation of the MacMillan Imidazolidinones

AU - Samulis, Leopold

AU - Tomkinson, Nicholas C.O.

PY - 2011/6/10

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AB - A general method for the preparation of the MacMillan imidazolidinones is described. Treatment of an α-amino amide with a carbonyl compound in refluxing chloroform in the presence of Yb(OTf)3 (1 mol%) provides convenient access to the corresponding imidazolidinones

KW - MacMillan imidazolidinones

KW - carbonyl

KW - chloroform

KW - imidazolidinones

U2 - 10.1016/j.tet.2011.04.009

DO - 10.1016/j.tet.2011.04.009

M3 - Article

SN - 0040-4020

VL - 67

SP - 4263

EP - 4267

JO - Tetrahedron

JF - Tetrahedron

IS - 23

ER -

Preparation of the MacMillan Imidazolidinones

Abstract

Keywords

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Research output

Organocatalysed transformations of alpha,beta-unsaturated carbonyl compoundsthrough iminium ion intermediates

Cite this