Preparation of the MacMillan Imidazolidinones

Leopold Samulis, Nicholas C.O. Tomkinson

Research output: Contribution to journalArticle

23 Citations (Scopus)
1267 Downloads (Pure)


A general method for the preparation of the MacMillan imidazolidinones is described. Treatment of an α-amino amide with a carbonyl compound in refluxing chloroform in the presence of Yb(OTf)3 (1 mol%) provides convenient access to the corresponding imidazolidinones
Original languageEnglish
Pages (from-to)4263-4267
Number of pages5
Issue number23
Publication statusPublished - 10 Jun 2011


  • MacMillan imidazolidinones
  • carbonyl
  • chloroform
  • imidazolidinones

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  • Research Output

    • 23 Citations
    • 1 Chapter

    Organocatalysed transformations of alpha,beta-unsaturated carbonyl compoundsthrough iminium ion intermediates

    Tomkinson, N. & Rowley, J., 14 Nov 2012, Asymmetric Synthesis : More Methods and Applications. Christmann, M. & Brase, S. (eds.). Weinheim, p. 29-34 6 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

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