Preliminary results on safety and activity of a randomized, double-blind, 2 x 2 trial of low-dose tamoxifen and fenretinide for breast cancer prevention in premenopausal women

A. Guerrieri-Gonzaga, C. Robertson, B. Bonanni, D. Serrano, M. Cazzaniga, S. Mora, M. Gulisano, H. Johansson

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Abstract

To determine whether low-dose tamoxifen and fenretinide have a synergistic effect on surrogate biomarkers, including circulating insulin-like growth factor I (IGF-I) and mammographic density, in premenopausal women at risk for breast cancer and to study drug safety.
Original languageEnglish
Pages (from-to)129-135
Number of pages6
JournalJournal of Clinical Oncology
Volume24
Issue number1
DOIs
Publication statusPublished - 1 Jan 2006

Keywords

  • tamoxifen
  • fenretinide
  • breast cancer prevention
  • results
  • statistics
  • premenopausal

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