Predicting hypocalcaemia post-thyroidectomy: a retrospective audit of results compared to a previously published nomogram in 64 patients treated at a district general hospital

A.I. Kaleva, R.W.A. Hone, T. Tikka, A. Al-lami, A. Balfour, I.J. Nixon

Research output: Contribution to journalLetter

Abstract

With the increasing incidence of thyroid cancer,1 total thyroidectomy and completion thyroidectomy are increasingly common in the NHS. Hypocalcaemia is an important complication of these procedures. The reported UK national incidence is 27% for total thyroidectomy and 29% for completion thyroidectomy.2 Predicting individualised patient risk would allow departments to focus resources on high‐risk patients, whilst considering low‐risk patients for early discharge.
Ali et al.3 described a nomogram to quantify patients' individualised risk of hypocalcaemia based on patient characteristics: age, gender, past medical and medication history, and preoperative investigations: calcium, alkaline phosphatase and creatinine levels. The nomogram achieved a 68% predictive accuracy in a US tertiary centre (Memorial Sloan Kettering Cancer Center, New York), but has not been tested in a UK population.
This study aims to report the rates of hypocalcaemia in a UK district general hospital and assess the clinical utility of the predictive nomogram in this population.
LanguageEnglish
Pages442-446
Number of pages5
JournalClinical Otolaryngology
Volume42
Issue number2
Early online date19 Dec 2015
DOIs
Publication statusPublished - 30 Apr 2017

Fingerprint

Nomograms
District Hospitals
Hypocalcemia
Thyroidectomy
General Hospitals
Patient Discharge
Incidence
Thyroid Neoplasms
Population
Alkaline Phosphatase
Creatinine
Calcium
Neoplasms

Keywords

  • thyroid cancer
  • hypocalcaemia

Cite this

@article{0107ebc790044a26ba3d7d77db943a84,
title = "Predicting hypocalcaemia post-thyroidectomy: a retrospective audit of results compared to a previously published nomogram in 64 patients treated at a district general hospital",
abstract = "With the increasing incidence of thyroid cancer,1 total thyroidectomy and completion thyroidectomy are increasingly common in the NHS. Hypocalcaemia is an important complication of these procedures. The reported UK national incidence is 27{\%} for total thyroidectomy and 29{\%} for completion thyroidectomy.2 Predicting individualised patient risk would allow departments to focus resources on high‐risk patients, whilst considering low‐risk patients for early discharge.Ali et al.3 described a nomogram to quantify patients' individualised risk of hypocalcaemia based on patient characteristics: age, gender, past medical and medication history, and preoperative investigations: calcium, alkaline phosphatase and creatinine levels. The nomogram achieved a 68{\%} predictive accuracy in a US tertiary centre (Memorial Sloan Kettering Cancer Center, New York), but has not been tested in a UK population.This study aims to report the rates of hypocalcaemia in a UK district general hospital and assess the clinical utility of the predictive nomogram in this population.",
keywords = "thyroid cancer, hypocalcaemia",
author = "A.I. Kaleva and R.W.A. Hone and T. Tikka and A. Al-lami and A. Balfour and I.J. Nixon",
year = "2017",
month = "4",
day = "30",
doi = "10.1111/coa.12610",
language = "English",
volume = "42",
pages = "442--446",
journal = "Clinical Otolaryngology",
issn = "1749-4478",
number = "2",

}

Predicting hypocalcaemia post-thyroidectomy : a retrospective audit of results compared to a previously published nomogram in 64 patients treated at a district general hospital. / Kaleva, A.I.; Hone, R.W.A.; Tikka, T.; Al-lami, A.; Balfour, A.; Nixon, I.J.

In: Clinical Otolaryngology, Vol. 42, No. 2, 30.04.2017, p. 442-446.

Research output: Contribution to journalLetter

TY - JOUR

T1 - Predicting hypocalcaemia post-thyroidectomy

T2 - Clinical Otolaryngology

AU - Kaleva, A.I.

AU - Hone, R.W.A.

AU - Tikka, T.

AU - Al-lami, A.

AU - Balfour, A.

AU - Nixon, I.J.

PY - 2017/4/30

Y1 - 2017/4/30

N2 - With the increasing incidence of thyroid cancer,1 total thyroidectomy and completion thyroidectomy are increasingly common in the NHS. Hypocalcaemia is an important complication of these procedures. The reported UK national incidence is 27% for total thyroidectomy and 29% for completion thyroidectomy.2 Predicting individualised patient risk would allow departments to focus resources on high‐risk patients, whilst considering low‐risk patients for early discharge.Ali et al.3 described a nomogram to quantify patients' individualised risk of hypocalcaemia based on patient characteristics: age, gender, past medical and medication history, and preoperative investigations: calcium, alkaline phosphatase and creatinine levels. The nomogram achieved a 68% predictive accuracy in a US tertiary centre (Memorial Sloan Kettering Cancer Center, New York), but has not been tested in a UK population.This study aims to report the rates of hypocalcaemia in a UK district general hospital and assess the clinical utility of the predictive nomogram in this population.

AB - With the increasing incidence of thyroid cancer,1 total thyroidectomy and completion thyroidectomy are increasingly common in the NHS. Hypocalcaemia is an important complication of these procedures. The reported UK national incidence is 27% for total thyroidectomy and 29% for completion thyroidectomy.2 Predicting individualised patient risk would allow departments to focus resources on high‐risk patients, whilst considering low‐risk patients for early discharge.Ali et al.3 described a nomogram to quantify patients' individualised risk of hypocalcaemia based on patient characteristics: age, gender, past medical and medication history, and preoperative investigations: calcium, alkaline phosphatase and creatinine levels. The nomogram achieved a 68% predictive accuracy in a US tertiary centre (Memorial Sloan Kettering Cancer Center, New York), but has not been tested in a UK population.This study aims to report the rates of hypocalcaemia in a UK district general hospital and assess the clinical utility of the predictive nomogram in this population.

KW - thyroid cancer

KW - hypocalcaemia

UR - http://www.scopus.com/inward/record.url?scp=84959206246&partnerID=8YFLogxK

U2 - 10.1111/coa.12610

DO - 10.1111/coa.12610

M3 - Letter

VL - 42

SP - 442

EP - 446

JO - Clinical Otolaryngology

JF - Clinical Otolaryngology

SN - 1749-4478

IS - 2

ER -