Precipitation stabilising compositions

Barry Moore (Inventor), Jan Vos (Inventor), Johann Partridge (Inventor)

Research output: Patent


The present invention relates to maintaining bioactive molecules in their native or substantially near-native form and preventing or reduce aggregation. In particular, the present invention relates to precipitation-protective or stabilising additives and a method of using said precipitation-protective/stabilising additives to protect and maintain the bioactive molecules in a native or substantially near-native form and to prevent or reduce aggregation during or following precipitation to form particles.
Original languageEnglish
Patent numberWO/2008/132439
IPCA61K 9/14 (2006.01)
Publication statusPublished - 6 Nov 2008


  • microcrystals
  • polar organic solvent
  • amino polyols
  • amino sugars


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