Abstract
The present invention relates to maintaining bioactive molecules in their native or substantially near-native form and preventing or reduce aggregation. In particular, the present invention relates to precipitation-protective or stabilising additives and a method of using said precipitation-protective/stabilising additives to protect and maintain the bioactive molecules in a native or substantially near-native form and to prevent or reduce aggregation during or following precipitation to form particles.
| Original language | English |
|---|---|
| Patent number | WO/2008/132439 |
| IPC | A61K 9/14 (2006.01) |
| Publication status | Published - 6 Nov 2008 |
Keywords
- microcrystals
- polar organic solvent
- amino polyols
- amino sugars