Precipitation stabilising compositions

Barry Moore; Jan Vos; Johann Partridge

Precipitation stabilising compositions

Barry Moore (Inventor), Jan Vos (Inventor), Johann Partridge (Inventor)

Pure And Applied Chemistry

Research output: Patent

Abstract

The present invention relates to maintaining bioactive molecules in their native or substantially near-native form and preventing or reduce aggregation. In particular, the present invention relates to precipitation-protective or stabilising additives and a method of using said precipitation-protective/stabilising additives to protect and maintain the bioactive molecules in a native or substantially near-native form and to prevent or reduce aggregation during or following precipitation to form particles.

Original language	English
Patent number	WO/2008/132439
IPC	A61K 9/14 (2006.01)
Publication status	Published - 6 Nov 2008

Keywords

microcrystals
polar organic solvent
amino polyols
amino sugars

Access to Document

http://www.patentlens.net/patentlens/patents.html?patnums=WO_2008_132439_A2&language=en&query=(WO_2008_132439%20in%20publication_number)&stemming=true&returnTo=quick.html%3Fquery%3DWO%252F2008%252F132439%26stemming%3Dtrue%26collections%3DUS_B%2CEP_B%2CAU_B%2CUS_A%2CWO_A%2CAU_A%26language%3Den%26pageLength%3D10

Cite this

Moore, B., Vos, J., & Partridge, J. (2008). IPC No. A61K 9/14 (2006.01). Precipitation stabilising compositions. (Patent No. WO/2008/132439).

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author = "Barry Moore and Jan Vos and Johann Partridge",

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AU - Vos, Jan

AU - Partridge, Johann

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AB - The present invention relates to maintaining bioactive molecules in their native or substantially near-native form and preventing or reduce aggregation. In particular, the present invention relates to precipitation-protective or stabilising additives and a method of using said precipitation-protective/stabilising additives to protect and maintain the bioactive molecules in a native or substantially near-native form and to prevent or reduce aggregation during or following precipitation to form particles.

KW - microcrystals

KW - polar organic solvent

KW - amino polyols

KW - amino sugars

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