Precipitation stabilising compositions

Barry Moore (Inventor), Jan Vos (Inventor), Johann Partridge (Inventor)

Research output: Patent

Abstract

The present invention relates to maintaining bioactive molecules in their native or substantially near-native form and preventing or reduce aggregation. In particular, the present invention relates to precipitation-protective or stabilising additives and a method of using said precipitation-protective/stabilising additives to protect and maintain the bioactive molecules in a native or substantially near-native form and to prevent or reduce aggregation during or following precipitation to form particles.
LanguageEnglish
Patent numberWO/2008/132439
IPCA61K 9/14 (2006.01)
Publication statusPublished - 6 Nov 2008

Keywords

  • microcrystals
  • polar organic solvent
  • amino polyols
  • amino sugars

Cite this

Moore, B., Vos, J., & Partridge, J. (2008). IPC No. A61K 9/14 (2006.01). Precipitation stabilising compositions. (Patent No. WO/2008/132439).
Moore, Barry (Inventor) ; Vos, Jan (Inventor) ; Partridge, Johann (Inventor). / Precipitation stabilising compositions. IPC No.: A61K 9/14 (2006.01). Patent No.: WO/2008/132439.
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author = "Barry Moore and Jan Vos and Johann Partridge",
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Moore, B, Vos, J & Partridge, J 2008, Precipitation stabilising compositions, Patent No. WO/2008/132439, IPC No. A61K 9/14 (2006.01).

Precipitation stabilising compositions. / Moore, Barry (Inventor); Vos, Jan (Inventor); Partridge, Johann (Inventor).

IPC No.: A61K 9/14 (2006.01). Patent No.: WO/2008/132439.

Research output: Patent

TY - PAT

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AU - Moore, Barry

AU - Vos, Jan

AU - Partridge, Johann

PY - 2008/11/6

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N2 - The present invention relates to maintaining bioactive molecules in their native or substantially near-native form and preventing or reduce aggregation. In particular, the present invention relates to precipitation-protective or stabilising additives and a method of using said precipitation-protective/stabilising additives to protect and maintain the bioactive molecules in a native or substantially near-native form and to prevent or reduce aggregation during or following precipitation to form particles.

AB - The present invention relates to maintaining bioactive molecules in their native or substantially near-native form and preventing or reduce aggregation. In particular, the present invention relates to precipitation-protective or stabilising additives and a method of using said precipitation-protective/stabilising additives to protect and maintain the bioactive molecules in a native or substantially near-native form and to prevent or reduce aggregation during or following precipitation to form particles.

KW - microcrystals

KW - polar organic solvent

KW - amino polyols

KW - amino sugars

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Moore B, Vos J, Partridge J, inventors. Precipitation stabilising compositions. A61K 9/14 (2006.01). 2008 Nov 6.