Potassium-alkyl magnesiates: synthesis, structures and Mg-H exchange applications of aromatic and heterocyclic substrates

Sharon E. Baillie; Tobias D. Bluemke; William Clegg; Alan R. Kennedy; Jan Klett; Luca Russo; Marco De Tullio; Eva Hevia

doi:10.1039/C4CC05305B

Potassium-alkyl magnesiates: synthesis, structures and Mg-H exchange applications of aromatic and heterocyclic substrates

Sharon E. Baillie, Tobias D. Bluemke, William Clegg, Alan R. Kennedy, Jan Klett, Luca Russo, Marco De Tullio, Eva Hevia

Pure And Applied Chemistry

Research output: Contribution to journal › Article

17 Citations (Scopus)

Abstract

Using structurally well-defined dipotassium- tetra(alkyl)magnesiates, a new straightforward methodology to promote regioselective Mg-H exchange reactions of a wide range of aromatic and heteroaromatic substrates is disclosed. Contacted ion pair intermediates are likely to be involved, with K being the key to facilitate the magnesiation processes.

Language	English
Pages	12859-12862
Number of pages	4
Journal	Chemical Communications
Volume	50
Early online date	3 Sep 2014
DOIs	10.1039/C4CC05305B
Publication status	Published - 3 Sep 2014

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Potassium

Ion exchange

Ions

Substrates

Keywords

dipotassium-tetra(alkyl)magnesiates
Mg–H exchange reactions
heteroaromatic substrates

Cite this

Baillie, S. E., Bluemke, T. D., Clegg, W., Kennedy, A. R., Klett, J., Russo, L., ... Hevia, E. (2014). Potassium-alkyl magnesiates: synthesis, structures and Mg-H exchange applications of aromatic and heterocyclic substrates. Chemical Communications, 50, 12859-12862. https://doi.org/10.1039/C4CC05305B

Baillie, Sharon E. ; Bluemke, Tobias D. ; Clegg, William ; Kennedy, Alan R. ; Klett, Jan ; Russo, Luca ; De Tullio, Marco ; Hevia, Eva. / Potassium-alkyl magnesiates : synthesis, structures and Mg-H exchange applications of aromatic and heterocyclic substrates. In: Chemical Communications. 2014 ; Vol. 50. pp. 12859-12862.

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Baillie, SE, Bluemke, TD, Clegg, W, Kennedy, AR, Klett, J, Russo, L, De Tullio, M & Hevia, E 2014, 'Potassium-alkyl magnesiates: synthesis, structures and Mg-H exchange applications of aromatic and heterocyclic substrates' Chemical Communications, vol. 50, pp. 12859-12862. https://doi.org/10.1039/C4CC05305B

Potassium-alkyl magnesiates : synthesis, structures and Mg-H exchange applications of aromatic and heterocyclic substrates. / Baillie, Sharon E.; Bluemke, Tobias D.; Clegg, William; Kennedy, Alan R.; Klett, Jan; Russo, Luca; De Tullio, Marco; Hevia, Eva.

In: Chemical Communications, Vol. 50, 03.09.2014, p. 12859-12862.

Research output: Contribution to journal › Article

TY - JOUR

T1 - Potassium-alkyl magnesiates

T2 - Chemical Communications

AU - Baillie, Sharon E.

AU - Bluemke, Tobias D.

AU - Clegg, William

AU - Kennedy, Alan R.

AU - Klett, Jan

AU - Russo, Luca

AU - De Tullio, Marco

AU - Hevia, Eva

PY - 2014/9/3

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AB - Using structurally well-defined dipotassium- tetra(alkyl)magnesiates, a new straightforward methodology to promote regioselective Mg-H exchange reactions of a wide range of aromatic and heteroaromatic substrates is disclosed. Contacted ion pair intermediates are likely to be involved, with K being the key to facilitate the magnesiation processes.

KW - dipotassium-tetra(alkyl)magnesiates

KW - Mg–H exchange reactions

KW - heteroaromatic substrates

UR - http://pubs.rsc.org/en/journals/journalissues/cc

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DO - 10.1039/C4CC05305B

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