Positively charged silver nanoparticles and their effect on surface-enhanced Raman scattering of dye-labelled oligonucleotides

Danny van Lierop, Zeljka Krpetic, Luca Guerrini, Iain A. Larmour, Jennifer A. Dougan, Karen Faulds, Duncan Graham

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Improved positively charged nanoparticles are described to provide a simplified SERS substrate for DNA detection. Complete flocculation of the nanoparticles is prevented due to the controlled analyte induced aggregation. This provides a stable aggregation state which significantly extends the analysis window simplifying DNA detection by SERS.

Original languageEnglish
Pages (from-to)8192-8194
Number of pages3
JournalChemical Communications
Volume48
Issue number66
DOIs
Publication statusPublished - 2012

Keywords

  • silver nanoparticles
  • surface-enhanced Raman scattering
  • Raman scattering
  • oligonucleotides

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