Portable microcontroller-based instrument for near-infrared spectroscopy

Mario Ettore Giardini, Mario Corti, Paolo Lago, Andrea Gelmetti

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

4 Citations (Scopus)

Abstract

Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. In particular, the technique can be particularly useful for muscular functional monitoring.
We present a portable NIRS research-grade acquisition system prototype, strictly dedicated to low-noise measurements during muscular exercise.
The prototype is able to control four LED sources and a detector. Such a number of sources allows for multipoint measurements or for multi-wavelength spectroscopy of tissue constituents other than oxygen, such as cytochrome aa3 oxidation.
The LEDs and the detector are mounted on separate probes, which carry also the relevant drivers and preamplifiers. By employing surface-mount technologies, probe size and weight are kept to a minimum. A single-chip mixed-signal RISC microcontroller performs source-to-detector multiplexing with a digital correlation technique. The acquired data are stored on an on-board 64 K EEPROM bank, and can be subsequently uploaded to a personal computer via serial port for further analysis.
The resulting instrument is compact and lightweight. Preliminary tests of the prototype on oxygen consumption during tourniquet-induced forearm ischaemia show adequate detectivity and time response.
LanguageEnglish
Title of host publicationDiagnostic, Guidance and Surgical-Assist Systems II
EditorsTuan Vo-Dinh, Warren S. Grundfest, David A. Benaron
Pages250-255
Number of pages6
DOIs
Publication statusPublished - 3 May 2000
EventConference on Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II - San Jose, United States
Duration: 25 Jan 200026 Jan 2000

Publication series

NameProceedings of SPIE
PublisherSPIE Press
Volume3911
ISSN (Print)0277-786X

Conference

ConferenceConference on Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II
CountryUnited States
CitySan Jose
Period25/01/0026/01/00

Fingerprint

Near infrared spectroscopy
Near-Infrared Spectroscopy
Microcontrollers
Detectors
Tourniquets
Light emitting diodes
Microcomputers
Electron Transport Complex IV
Forearm
Oxygen Consumption
Tissue
Noise
Spectrum Analysis
Reduced instruction set computing
Oxygen
Oxygenation
Ischemia
Surface mount technology
Hemodynamics
Technology

Keywords

  • portable NIRS
  • LED
  • digital
  • portable microcontroller-based instrument
  • near-infrared spectroscopy

Cite this

Giardini, M. E., Corti, M., Lago, P., & Gelmetti, A. (2000). Portable microcontroller-based instrument for near-infrared spectroscopy. In T. Vo-Dinh, W. S. Grundfest, & D. A. Benaron (Eds.), Diagnostic, Guidance and Surgical-Assist Systems II (pp. 250-255). (Proceedings of SPIE; Vol. 3911). https://doi.org/10.1117/12.384910
Giardini, Mario Ettore ; Corti, Mario ; Lago, Paolo ; Gelmetti, Andrea. / Portable microcontroller-based instrument for near-infrared spectroscopy. Diagnostic, Guidance and Surgical-Assist Systems II. editor / Tuan Vo-Dinh ; Warren S. Grundfest ; David A. Benaron. 2000. pp. 250-255 (Proceedings of SPIE).
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Giardini, ME, Corti, M, Lago, P & Gelmetti, A 2000, Portable microcontroller-based instrument for near-infrared spectroscopy. in T Vo-Dinh, WS Grundfest & DA Benaron (eds), Diagnostic, Guidance and Surgical-Assist Systems II. Proceedings of SPIE, vol. 3911, pp. 250-255, Conference on Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II, San Jose, United States, 25/01/00. https://doi.org/10.1117/12.384910

Portable microcontroller-based instrument for near-infrared spectroscopy. / Giardini, Mario Ettore; Corti, Mario; Lago, Paolo; Gelmetti, Andrea.

Diagnostic, Guidance and Surgical-Assist Systems II. ed. / Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron. 2000. p. 250-255 (Proceedings of SPIE; Vol. 3911).

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

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N2 - Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. In particular, the technique can be particularly useful for muscular functional monitoring.We present a portable NIRS research-grade acquisition system prototype, strictly dedicated to low-noise measurements during muscular exercise.The prototype is able to control four LED sources and a detector. Such a number of sources allows for multipoint measurements or for multi-wavelength spectroscopy of tissue constituents other than oxygen, such as cytochrome aa3 oxidation.The LEDs and the detector are mounted on separate probes, which carry also the relevant drivers and preamplifiers. By employing surface-mount technologies, probe size and weight are kept to a minimum. A single-chip mixed-signal RISC microcontroller performs source-to-detector multiplexing with a digital correlation technique. The acquired data are stored on an on-board 64 K EEPROM bank, and can be subsequently uploaded to a personal computer via serial port for further analysis.The resulting instrument is compact and lightweight. Preliminary tests of the prototype on oxygen consumption during tourniquet-induced forearm ischaemia show adequate detectivity and time response.

AB - Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. In particular, the technique can be particularly useful for muscular functional monitoring.We present a portable NIRS research-grade acquisition system prototype, strictly dedicated to low-noise measurements during muscular exercise.The prototype is able to control four LED sources and a detector. Such a number of sources allows for multipoint measurements or for multi-wavelength spectroscopy of tissue constituents other than oxygen, such as cytochrome aa3 oxidation.The LEDs and the detector are mounted on separate probes, which carry also the relevant drivers and preamplifiers. By employing surface-mount technologies, probe size and weight are kept to a minimum. A single-chip mixed-signal RISC microcontroller performs source-to-detector multiplexing with a digital correlation technique. The acquired data are stored on an on-board 64 K EEPROM bank, and can be subsequently uploaded to a personal computer via serial port for further analysis.The resulting instrument is compact and lightweight. Preliminary tests of the prototype on oxygen consumption during tourniquet-induced forearm ischaemia show adequate detectivity and time response.

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Giardini ME, Corti M, Lago P, Gelmetti A. Portable microcontroller-based instrument for near-infrared spectroscopy. In Vo-Dinh T, Grundfest WS, Benaron DA, editors, Diagnostic, Guidance and Surgical-Assist Systems II. 2000. p. 250-255. (Proceedings of SPIE). https://doi.org/10.1117/12.384910