Plasmonic ELISA for the detection of gp120 at ultralow concentrations with the naked eye

D. Cecchin, Roberto De La Rica, R.E.S. Bain, Michael W. Finnis, M.M. Stevens, G. Battaglia

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The technique of plasmonic ELISA is utilised here to detect the HIV-1 protein gp120 with the ultralow limit of detection of 8 × 10−20 M (10−17 g mL−1) in an independent laboratory. It was corroborated that changes in the concentration of hydrogen peroxide as small as 0.05 μM could lead to nanoparticle solutions of completely different tonality.
Original languageEnglish
Pages (from-to)9559-9562
Number of pages4
JournalNanoscale
Volume6
Issue number16
Early online date5 May 2014
DOIs
Publication statusPublished - 2014

Keywords

  • plasmonic ELISA
  • ultralow concentrations
  • nanoparticle solutions

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