Phytochemical and antifungal studies on Terminalia mollis and Terminalia brachystemma

Manjuan Liu, David R. Katerere, Alexander I. Gray, Veronique Seidel

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Phytochemical investigation of the stem bark of Terminalia mollis afforded friedelin (1), catechin with epicatechin (2), gallocatechin with epigallocatechin (3) and 3-O-methylellagic acid 4'-O-alpha-rhamnopyranoside (4). Arjunolic acid with 2 alpha, 3 beta, 23-trihydroxy-urs-12-en-28-oic acid (5), 2 alpha-hydroxyursolic acid (6), gallic acid (7), chebulanin (8) and 2 ''-O-galloylvitexin (9) were isolated from the leaf. Chebulanin (8), betulinic acid (10), ursolic acid (11), catechin (12), isoorientin (13), orientin (14), isovitexin (15) and punicalagin (16) were isolated from Terminalia brachystemma leaf The first full unambiguous NMR assignments for (4) and (8), and revised assignments for (9), are reported. Compound (16) showed good activity against three Candida species.
Original languageEnglish
Pages (from-to)369-373
Number of pages4
JournalFitoterapia
Volume80
Issue number6
Early online date14 May 2009
DOIs
Publication statusPublished - 1 Sep 2009

Keywords

  • terminalia mollis
  • terminalia brachystemma
  • combretaceae
  • punicalagin
  • antifungal activity

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