Phylogenetic analysis of Klebsiella pneumoniae from hospitalized children, Pakistan

Hasan Ejaz, Nancy Wang, Jonathan J. Wilksch, Andrew J. Page, Hanwei Cao, Shruti Gujaran, Jacqueline A. Keane, Trevor Lithgow, Ikram Ul-Haq, Gordon Dougan, Richard A. Strugnell*, Eva Heinz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Klebsiella pneumoniae shows increasing emergence of multidrug-resistant lineages, including strains resistant to all available antimicrobial drugs. We conducted whole-genome sequencing of 178 highly drug-resistant isolates from a tertiary hospital in Lahore, Pakistan. Phylogenetic analyses to place these isolates into global context demonstrate the expansion of multiple independent lineages, including K. quasipneumoniae.

Original languageEnglish
Pages (from-to)1872-1875
Number of pages4
JournalEmerging Infectious Diseases
Volume23
Issue number11
DOIs
Publication statusPublished - 1 Nov 2017

Funding

This work was supported by National Health and Medical Research Council program grants (0606788 to R.A.S. and T.L.; 1092262 to R.A.S., G.D., and T.L.); the Wellcome Trust (206194); and the Higher Education Commission of Pakistan and The Children’s Hospital & The Institute of Child Health, Lahore, Pakistan. H.E. was supported by a scholarship from Higher Education Commission Pakistan under the International Research Support Initiative Program.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Klebsiella pneumoniae
  • children
  • antimicrobial resistance

Fingerprint

Dive into the research topics of 'Phylogenetic analysis of Klebsiella pneumoniae from hospitalized children, Pakistan'. Together they form a unique fingerprint.

Cite this