Phosphatase/temperature responsive poly(2-isopropyl-2-oxazoline)

P. F. Caponi, X. P. Qiu, F. Vilela, F. M. Winnik, R. V. Ulijn

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

We demonstrate a strategy for producing polymer bioconjugates which display both enzymatic and thermal responsiveness. This is achieved by combining the thermo-responsive properties of poly(2-isopropyl-2-oxazoline) (PiPrOx) with the self-assembly properties of fluorenylmethoxycarbonyl-tyrosine (Fmoc-Y), controlled by a phosphatase triggered mechanism.
Original languageEnglish
Pages (from-to)306-308
Number of pages3
JournalPolymer Chemistry
Volume2
DOIs
Publication statusPublished - 2011

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Keywords

  • copolymers
  • polymers
  • hydrogels
  • proteins
  • cells
  • liposomes
  • polymerization
  • TIC - Bionanotechnology

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