Phosphatase/temperature responsive poly(2-isopropyl-2-oxazoline)

P. F. Caponi, X. P. Qiu, F. Vilela, F. M. Winnik, R. V. Ulijn

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

We demonstrate a strategy for producing polymer bioconjugates which display both enzymatic and thermal responsiveness. This is achieved by combining the thermo-responsive properties of poly(2-isopropyl-2-oxazoline) (PiPrOx) with the self-assembly properties of fluorenylmethoxycarbonyl-tyrosine (Fmoc-Y), controlled by a phosphatase triggered mechanism.
LanguageEnglish
Pages306-308
Number of pages3
JournalPolymer Chemistry
Volume2
DOIs
Publication statusPublished - 2011

Fingerprint

Phosphatases
Phosphoric Monoester Hydrolases
Self assembly
Tyrosine
Polymers
Hot Temperature
Temperature
poly(2-isopropyl-2-oxazoline)

Keywords

  • copolymers
  • polymers
  • hydrogels
  • proteins
  • cells
  • liposomes
  • polymerization
  • TIC - Bionanotechnology

Cite this

Caponi, P. F. ; Qiu, X. P. ; Vilela, F. ; Winnik, F. M. ; Ulijn, R. V. / Phosphatase/temperature responsive poly(2-isopropyl-2-oxazoline). In: Polymer Chemistry. 2011 ; Vol. 2. pp. 306-308.
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Phosphatase/temperature responsive poly(2-isopropyl-2-oxazoline). / Caponi, P. F.; Qiu, X. P.; Vilela, F.; Winnik, F. M.; Ulijn, R. V.

In: Polymer Chemistry, Vol. 2, 2011, p. 306-308.

Research output: Contribution to journalArticle

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AU - Qiu, X. P.

AU - Vilela, F.

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AU - Ulijn, R. V.

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KW - polymers

KW - hydrogels

KW - proteins

KW - cells

KW - liposomes

KW - polymerization

KW - TIC - Bionanotechnology

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DO - 10.1039/c0py00291g

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T2 - Polymer Chemistry

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