We demonstrate a strategy for producing polymer bioconjugates which display both enzymatic and thermal responsiveness. This is achieved by combining the thermo-responsive properties of poly(2-isopropyl-2-oxazoline) (PiPrOx) with the self-assembly properties of fluorenylmethoxycarbonyl-tyrosine (Fmoc-Y), controlled by a phosphatase triggered mechanism.
- TIC - Bionanotechnology
Caponi, P. F., Qiu, X. P., Vilela, F., Winnik, F. M., & Ulijn, R. V. (2011). Phosphatase/temperature responsive poly(2-isopropyl-2-oxazoline). Polymer Chemistry, 2, 306-308. https://doi.org/10.1039/c0py00291g