Pharmacy-implemented guidelines on switching from intravenous to oral antibiotics: an intervention study

C.M. McLaughlin, N. Bodasing, A.C. Boyter, C. Fenelon, J.G. Fox, A.V. Seaton

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A high proportion of medical in-patients in the UK receive intravenous (IV) antibiotic therapy. This may be inappropriate in non-severe infections, or unnecessarily prolonged. Data relating to infection and antibiotic therapy were collected for 4 weeks pre-intervention (group 1) and 4 weeks post intervention (group 2). Six months later, data were collected for a further 4 weeks following a second intervention (group 3). Interventions consisted of pharmacy-led implementation of guidelines incorporating criteria for IV therapy and switching to the oral route. The second intervention also included pharmacy-initiated feedback on prescribing. The main outcome measures were IV antibiotic duration, and appropriateness of the IV route and switching.
Original languageEnglish
Pages (from-to)745-752
Number of pages7
JournalQuarterly Journal of Medicine
Issue number10
Publication statusPublished - 26 Aug 2005


  • Pharmacy guidelines
  • intravenous medication
  • oral antibiotics
  • study

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