Pharmacological remodelling of human atrial k+ currents by chronic beta-blockade

G. Marshall, A.C. Rankin, K.A. Kane, A.J. Workman

Research output: Contribution to journalArticle

Abstract

The chronic treatment of patients with a beta-blocker is associated with prolongation of the atrial action potential duration (APD), potentially contributing to its ability to prevent atrial fibrillation (AF). This may involve pharmacological remodelling of atrial K+ currents which affect APD. This project aimed to test the hypothesis that various characteristics of human atrial K+ currents, including voltage, time and rate dependency, differ between patients treated and not treated with a beta-blocker.
LanguageEnglish
Article number389
Pages30-30
Number of pages1
JournalEuropean Heart Journal
Volume27
Issue numberSupplement 1
DOIs
Publication statusPublished - Aug 2006
EventWorld Congress of Cardiology 2006 - Barcelona, Spain
Duration: 2 Sep 20066 Sep 2006

Fingerprint

Atrial Remodeling
Action Potentials
Pharmacology
Atrial Fibrillation
Therapeutics

Keywords

  • beta blocker
  • pharmacology
  • human atrial K+ currents

Cite this

Marshall, G., Rankin, A. C., Kane, K. A., & Workman, A. J. (2006). Pharmacological remodelling of human atrial k+ currents by chronic beta-blockade. European Heart Journal , 27(Supplement 1), 30-30. [389]. https://doi.org/10.1093/eurheartj/ehl212
Marshall, G. ; Rankin, A.C. ; Kane, K.A. ; Workman, A.J. / Pharmacological remodelling of human atrial k+ currents by chronic beta-blockade. In: European Heart Journal . 2006 ; Vol. 27, No. Supplement 1. pp. 30-30.
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Marshall, G, Rankin, AC, Kane, KA & Workman, AJ 2006, 'Pharmacological remodelling of human atrial k+ currents by chronic beta-blockade' European Heart Journal , vol. 27, no. Supplement 1, 389, pp. 30-30. https://doi.org/10.1093/eurheartj/ehl212

Pharmacological remodelling of human atrial k+ currents by chronic beta-blockade. / Marshall, G.; Rankin, A.C.; Kane, K.A.; Workman, A.J.

In: European Heart Journal , Vol. 27, No. Supplement 1, 389, 08.2006, p. 30-30.

Research output: Contribution to journalArticle

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