Pharmaceutical applications of terahertz spectroscopy and imaging

Daniel Markl, Michael T. Ruggiero, J. Axel Zeitler

Research output: Contribution to specialist publicationArticle

19 Citations (Scopus)

Abstract

Terahertz spectroscopy and imaging techniques have advanced the chemical and physical characterisation of active pharmaceutical ingredients (APIs), excipients and final solid dosage forms. Terahertz radiation can be used to investigate both chemical and solid structures, as well as provide information on the bulk morphology of pharmaceutical materials. The penetrating and non-destructive properties of terahertz light, coupled with its high acquisition rate, makes this technology a promising candidate for process analytical technology (PAT) applications.

Original languageEnglish
Pages45-50
Number of pages6
Volume21
No.4
Specialist publicationEuropean Pharmaceutical Review
Publication statusPublished - 1 Jan 2016

Keywords

  • terahertz spectroscopy
  • imaging techniques
  • active pharmaceutical ingredients
  • solid dosage forms

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