Persistent severe hiccups after dexamethasone intravenous administration

Nantawit Sugandhavesa; Passakorn Sawaddiruk; Torphong Bunmaprasert; Sintip Pattanakuhar; Siriporn C. Chattipakorn; Nipon Chattipakorn

doi:10.12659/AJCR.915282

Persistent severe hiccups after dexamethasone intravenous administration

Nantawit Sugandhavesa, Passakorn Sawaddiruk, Torphong Bunmaprasert, Sintip Pattanakuhar, Siriporn C. Chattipakorn, Nipon Chattipakorn

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

BACKGROUND: Hiccups induced by steroids administration is not common. Although it is not life-threatening and is always recognized as a transient and minor complication, it can be severely uncomfortable and significantly diminished patient quality of life. In this case report, persistent hiccups were observed in 2 middle-aged Thai men receiving low-dose intravenous dexamethasone. This case report highlights the awareness of severe dexamethasone-induced hiccups.

CASE REPORT: A 49-year-old man and a 38-year-old man were admitted to our hospital and received IV dexamethasone. The hiccups started after each patient received a single dose of dexamethasone. The frequency and severity of their hiccups increased over time during dexamethasone treatment. Hiccups still continued to occur despite the discontinuation of dexamethasone and lasted for 72 h after drug termination.

CONCLUSIONS: Dexamethasone can cause persistent hiccups. Although hiccups are not life-threatening, it should not be neglected since it can be severely uncomfortable and significantly diminish patient quality of life. Termination of dexamethasone can gradually relieve hiccups. Dexamethasone should be used cautiously and clinicians must be aware of this undesirable effect.

Original language	English
Pages (from-to)	628-630
Number of pages	3
Journal	American Journal of Case Reports
Volume	20
DOIs	https://doi.org/10.12659/AJCR.915282
Publication status	Published - 30 Apr 2019

Keywords

dexamethasone
drug-related side effects
adverse reactions
hiccup

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10.12659/AJCR.915282Licence: CC BY-NC-ND 4.0

Sugandhavesa-etal-AJCR-2019-Persistent-severe-hiccups-after-dexamethasone-intravenous-administrationFinal published version, 1.08 MBLicence: CC BY-NC-ND 4.0

Cite this

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title = "Persistent severe hiccups after dexamethasone intravenous administration",

abstract = "BACKGROUND: Hiccups induced by steroids administration is not common. Although it is not life-threatening and is always recognized as a transient and minor complication, it can be severely uncomfortable and significantly diminished patient quality of life. In this case report, persistent hiccups were observed in 2 middle-aged Thai men receiving low-dose intravenous dexamethasone. This case report highlights the awareness of severe dexamethasone-induced hiccups.CASE REPORT: A 49-year-old man and a 38-year-old man were admitted to our hospital and received IV dexamethasone. The hiccups started after each patient received a single dose of dexamethasone. The frequency and severity of their hiccups increased over time during dexamethasone treatment. Hiccups still continued to occur despite the discontinuation of dexamethasone and lasted for 72 h after drug termination.CONCLUSIONS: Dexamethasone can cause persistent hiccups. Although hiccups are not life-threatening, it should not be neglected since it can be severely uncomfortable and significantly diminish patient quality of life. Termination of dexamethasone can gradually relieve hiccups. Dexamethasone should be used cautiously and clinicians must be aware of this undesirable effect.",

keywords = "dexamethasone, drug-related side effects, adverse reactions, hiccup",

author = "Nantawit Sugandhavesa and Passakorn Sawaddiruk and Torphong Bunmaprasert and Sintip Pattanakuhar and Chattipakorn, {Siriporn C.} and Nipon Chattipakorn",

year = "2019",

month = apr,

day = "30",

doi = "10.12659/AJCR.915282",

language = "English",

volume = "20",

pages = "628--630",

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TY - JOUR

T1 - Persistent severe hiccups after dexamethasone intravenous administration

AU - Sugandhavesa, Nantawit

AU - Sawaddiruk, Passakorn

AU - Bunmaprasert, Torphong

AU - Pattanakuhar, Sintip

AU - Chattipakorn, Siriporn C.

AU - Chattipakorn, Nipon

PY - 2019/4/30

Y1 - 2019/4/30

N2 - BACKGROUND: Hiccups induced by steroids administration is not common. Although it is not life-threatening and is always recognized as a transient and minor complication, it can be severely uncomfortable and significantly diminished patient quality of life. In this case report, persistent hiccups were observed in 2 middle-aged Thai men receiving low-dose intravenous dexamethasone. This case report highlights the awareness of severe dexamethasone-induced hiccups.CASE REPORT: A 49-year-old man and a 38-year-old man were admitted to our hospital and received IV dexamethasone. The hiccups started after each patient received a single dose of dexamethasone. The frequency and severity of their hiccups increased over time during dexamethasone treatment. Hiccups still continued to occur despite the discontinuation of dexamethasone and lasted for 72 h after drug termination.CONCLUSIONS: Dexamethasone can cause persistent hiccups. Although hiccups are not life-threatening, it should not be neglected since it can be severely uncomfortable and significantly diminish patient quality of life. Termination of dexamethasone can gradually relieve hiccups. Dexamethasone should be used cautiously and clinicians must be aware of this undesirable effect.

AB - BACKGROUND: Hiccups induced by steroids administration is not common. Although it is not life-threatening and is always recognized as a transient and minor complication, it can be severely uncomfortable and significantly diminished patient quality of life. In this case report, persistent hiccups were observed in 2 middle-aged Thai men receiving low-dose intravenous dexamethasone. This case report highlights the awareness of severe dexamethasone-induced hiccups.CASE REPORT: A 49-year-old man and a 38-year-old man were admitted to our hospital and received IV dexamethasone. The hiccups started after each patient received a single dose of dexamethasone. The frequency and severity of their hiccups increased over time during dexamethasone treatment. Hiccups still continued to occur despite the discontinuation of dexamethasone and lasted for 72 h after drug termination.CONCLUSIONS: Dexamethasone can cause persistent hiccups. Although hiccups are not life-threatening, it should not be neglected since it can be severely uncomfortable and significantly diminish patient quality of life. Termination of dexamethasone can gradually relieve hiccups. Dexamethasone should be used cautiously and clinicians must be aware of this undesirable effect.

KW - dexamethasone

KW - drug-related side effects

KW - adverse reactions

KW - hiccup

U2 - 10.12659/AJCR.915282

DO - 10.12659/AJCR.915282

M3 - Article

VL - 20

SP - 628

EP - 630

JO - American Journal of Case Reports

JF - American Journal of Case Reports

ER -

Persistent severe hiccups after dexamethasone intravenous administration

Abstract

Keywords

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