Perfusion optimisation for design of vascular grafts used in the treatment of aortic disease

Scott Black, Konstantinos Ritos, Craig Maclean , Robbie Brodie, Asimina Kazakidi

Research output: Contribution to conferenceAbstractpeer-review


Regions of the aortic arch affected by an aneurysm or dissection may require surgical intervention using vascular grafts, which includes a means of re-perfusing the supra-aortic branch vessels. However, graft configuration to ensure optimal post-surgical perfusion is currently poorly understood. Therefore, enhanced understanding of perfusion in patient-specific cases is critical to improving clinical practice and patient outcomes. In this work, a combination of computational and experimental models of the aortic arch were created to investigate the pre-surgical haemodynamics of the aortic arch, using a coupled 3D-0D numerical framework to simulate a range of downstream conditions, both healthy and pathological.
Original languageEnglish
Number of pages1
Publication statusPublished - 12 Dec 2019
EventCMALS One Health Workshop - University of Strathclyde, Glasgow, United Kingdom
Duration: 12 Dec 201912 Dec 2019


WorkshopCMALS One Health Workshop
Country/TerritoryUnited Kingdom


  • aortic arch
  • patient outcomes
  • haemodynamics


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