Peptoids for biomaterials science

King Hang Aaron Lau

doi:10.1039/c3bm60269a

Peptoids for biomaterials science

King Hang Aaron Lau^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

315 Downloads (Pure)

Abstract

Poly(N-substituted glycine) "peptoids" have conventionally been exploited for drug discovery and therapeutics due to their structural similarity to peptides, protease resistance, and relative ease of synthesis. This mini-review highlights recent reports of peptoid self-assembled nanostructures and macromolecular interfaces relevant to biomaterials science. The results illustrate how the versatility of peptoid design and synthesis could be exploited to generate multifunctional, modular and precisely tunable biointerfaces and biomaterials.

Original language	English
Pages (from-to)	627-633
Number of pages	7
Journal	Biomaterials Science
Volume	2
Issue number	5
Early online date	16 Jan 2014
DOIs	https://doi.org/10.1039/c3bm60269a
Publication status	Published - Jan 2014

Keywords

peptoids
poly(N-substituted glycine)
self-assembled nanostructures
biomaterials science

Access to Document

10.1039/c3bm60269a

Lau-BS2014-peptoids-for-biomaterials-scienceAccepted author manuscript, 5.53 MB

Cite this

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title = "Peptoids for biomaterials science",

abstract = "Poly(N-substituted glycine) {"}peptoids{"} have conventionally been exploited for drug discovery and therapeutics due to their structural similarity to peptides, protease resistance, and relative ease of synthesis. This mini-review highlights recent reports of peptoid self-assembled nanostructures and macromolecular interfaces relevant to biomaterials science. The results illustrate how the versatility of peptoid design and synthesis could be exploited to generate multifunctional, modular and precisely tunable biointerfaces and biomaterials.",

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AB - Poly(N-substituted glycine) "peptoids" have conventionally been exploited for drug discovery and therapeutics due to their structural similarity to peptides, protease resistance, and relative ease of synthesis. This mini-review highlights recent reports of peptoid self-assembled nanostructures and macromolecular interfaces relevant to biomaterials science. The results illustrate how the versatility of peptoid design and synthesis could be exploited to generate multifunctional, modular and precisely tunable biointerfaces and biomaterials.

KW - peptoids

KW - poly(N-substituted glycine)

KW - self-assembled nanostructures

KW - biomaterials science

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VL - 2

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Peptoids for biomaterials science

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

257th American Chemical Society National Meeting - Orlando

Keynote lecture at the workshop on Recent Advances on Bio-inspired Nanomaterials for Environmental Applications Bio-inspired (Centre for the Environment)

Invited lecture at IMRE Singapore (Advanced Surfaces Lecture Series)

Cite this

Peptoids for biomaterials science

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Research output

Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

Activities

257th American Chemical Society National Meeting - Orlando

Keynote lecture at the workshop on Recent Advances on Bio-inspired Nanomaterials for Environmental Applications Bio-inspired (Centre for the Environment)

Invited lecture at IMRE Singapore (Advanced Surfaces Lecture Series)

Cite this