Peptoids for biomaterials science

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Poly(N-substituted glycine) "peptoids" have conventionally been exploited for drug discovery and therapeutics due to their structural similarity to peptides, protease resistance, and relative ease of synthesis. This mini-review highlights recent reports of peptoid self-assembled nanostructures and macromolecular interfaces relevant to biomaterials science. The results illustrate how the versatility of peptoid design and synthesis could be exploited to generate multifunctional, modular and precisely tunable biointerfaces and biomaterials.

LanguageEnglish
Pages627-633
Number of pages7
JournalBiomaterials Science
Volume2
Issue number5
Early online date16 Jan 2014
DOIs
Publication statusPublished - Jan 2014

Fingerprint

Peptoids
Biocompatible Materials
Biomaterials
N-substituted Glycines
Peptides
Amino acids
Nanostructures
Peptide Hydrolases

Keywords

  • peptoids
  • poly(N-substituted glycine)
  • self-assembled nanostructures
  • biomaterials science

Cite this

@article{aa6610884beb439d94f0a866ebcc1d57,
title = "Peptoids for biomaterials science",
abstract = "Poly(N-substituted glycine) {"}peptoids{"} have conventionally been exploited for drug discovery and therapeutics due to their structural similarity to peptides, protease resistance, and relative ease of synthesis. This mini-review highlights recent reports of peptoid self-assembled nanostructures and macromolecular interfaces relevant to biomaterials science. The results illustrate how the versatility of peptoid design and synthesis could be exploited to generate multifunctional, modular and precisely tunable biointerfaces and biomaterials.",
keywords = "peptoids, poly(N-substituted glycine), self-assembled nanostructures, biomaterials science",
author = "Lau, {King Hang Aaron}",
year = "2014",
month = "1",
doi = "10.1039/c3bm60269a",
language = "English",
volume = "2",
pages = "627--633",
journal = "Biomaterials Science",
issn = "2047-4830",
publisher = "Royal Society of Chemistry",
number = "5",

}

Peptoids for biomaterials science. / Lau, King Hang Aaron.

In: Biomaterials Science, Vol. 2, No. 5, 01.2014, p. 627-633.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Peptoids for biomaterials science

AU - Lau, King Hang Aaron

PY - 2014/1

Y1 - 2014/1

N2 - Poly(N-substituted glycine) "peptoids" have conventionally been exploited for drug discovery and therapeutics due to their structural similarity to peptides, protease resistance, and relative ease of synthesis. This mini-review highlights recent reports of peptoid self-assembled nanostructures and macromolecular interfaces relevant to biomaterials science. The results illustrate how the versatility of peptoid design and synthesis could be exploited to generate multifunctional, modular and precisely tunable biointerfaces and biomaterials.

AB - Poly(N-substituted glycine) "peptoids" have conventionally been exploited for drug discovery and therapeutics due to their structural similarity to peptides, protease resistance, and relative ease of synthesis. This mini-review highlights recent reports of peptoid self-assembled nanostructures and macromolecular interfaces relevant to biomaterials science. The results illustrate how the versatility of peptoid design and synthesis could be exploited to generate multifunctional, modular and precisely tunable biointerfaces and biomaterials.

KW - peptoids

KW - poly(N-substituted glycine)

KW - self-assembled nanostructures

KW - biomaterials science

UR - http://www.scopus.com/inward/record.url?scp=84897505852&partnerID=8YFLogxK

UR - http://pubs.rsc.org/en/journals/journalissues/bm

U2 - 10.1039/c3bm60269a

DO - 10.1039/c3bm60269a

M3 - Article

VL - 2

SP - 627

EP - 633

JO - Biomaterials Science

T2 - Biomaterials Science

JF - Biomaterials Science

SN - 2047-4830

IS - 5

ER -