Abstract
This article explores recent advances in the design and engineering of materials wholly or principally constructed from peptides. We focus on materials that are able to respond to changes in their environment (pH, ionic strength, temperature, light, oxidation/reduction state, presence of small molecules or the catalytic activity of enzymes) by altering their macromolecular structure. Such peptide-based responsive biomaterials have exciting prospects for a variety of biomedical and bionanotechnology applications in drug delivery, bio-sensing and regenerative medicine.
Original language | English |
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Pages (from-to) | 822-835 |
Number of pages | 14 |
Journal | Soft Matter |
Volume | 2 |
Issue number | 10 |
Early online date | 25 Aug 2006 |
DOIs | |
Publication status | Published - 7 Oct 2006 |
Keywords
- peptide-based
- stimuli-responsive biomaterials
- supramolecular hydrogels
- elastin-like polypeptide
- cross-linker
- nanofibers