Peptide-based stimuli-responsive biomaterials

Robert J. Mart, Rachel D. Osborne, Molly M. Stevens, Rein V. Ulijn

Research output: Contribution to journalLiterature review

416 Citations (Scopus)

Abstract

This article explores recent advances in the design and engineering of materials wholly or principally constructed from peptides. We focus on materials that are able to respond to changes in their environment (pH, ionic strength, temperature, light, oxidation/reduction state, presence of small molecules or the catalytic activity of enzymes) by altering their macromolecular structure. Such peptide-based responsive biomaterials have exciting prospects for a variety of biomedical and bionanotechnology applications in drug delivery, bio-sensing and regenerative medicine.

LanguageEnglish
Pages822-835
Number of pages14
JournalSoft Matter
Volume2
Issue number10
Early online date25 Aug 2006
DOIs
Publication statusPublished - 7 Oct 2006

Fingerprint

Biocompatible Materials
stimuli
peptides
Peptides
Ionic strength
Drug delivery
medicine
catalytic activity
enzymes
Catalyst activity
delivery
drugs
engineering
oxidation
Molecules
Enzymes
molecules
Temperature
temperature
Regenerative Medicine

Keywords

  • peptide-based
  • stimuli-responsive biomaterials
  • supramolecular hydrogels
  • elastin-like polypeptide
  • cross-linker
  • nanofibers

Cite this

Mart, R. J., Osborne, R. D., Stevens, M. M., & Ulijn, R. V. (2006). Peptide-based stimuli-responsive biomaterials. Soft Matter, 2(10), 822-835. https://doi.org/10.1039/b607706d
Mart, Robert J. ; Osborne, Rachel D. ; Stevens, Molly M. ; Ulijn, Rein V. / Peptide-based stimuli-responsive biomaterials. In: Soft Matter. 2006 ; Vol. 2, No. 10. pp. 822-835.
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Mart, RJ, Osborne, RD, Stevens, MM & Ulijn, RV 2006, 'Peptide-based stimuli-responsive biomaterials' Soft Matter, vol. 2, no. 10, pp. 822-835. https://doi.org/10.1039/b607706d

Peptide-based stimuli-responsive biomaterials. / Mart, Robert J.; Osborne, Rachel D.; Stevens, Molly M.; Ulijn, Rein V.

In: Soft Matter, Vol. 2, No. 10, 07.10.2006, p. 822-835.

Research output: Contribution to journalLiterature review

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