Patient-specific blood flow simulations in the pulmonary bifurcation of patients with tetralogy of fallot

M. Boumpouli; E. Sauvage; C. Capelli; S. Schievano; T. Gourlay; A. Kazakidi

Patient-specific blood flow simulations in the pulmonary bifurcation of patients with tetralogy of fallot

M. Boumpouli, E. Sauvage, C. Capelli, S. Schievano, T. Gourlay, A. Kazakidi

Biomedical Engineering

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Abstract

Dysfunction of the pulmonary valve and narrowing of the branch pulmonary arteries are common chronic complications in adult patients with tetralogy of Fallot; the most common cyanotic congenital heart disease with an estimate prevalence 1 in 3000 live births. Clinical consequences include, but are not limited to, abnormal lung development and elevated pulmonary vascular resistance. It is, therefore, crucial to better understand and characterise the haemodynamic environment in the pulmonary bifurcation to better diagnose and treat these patients. In this study, we have focused on investigating the blood flow dynamics in patient-specific geometries of the pulmonary bifurcation by means of computational models.

Original language	English
Number of pages	1
Publication status	Published - 19 Jul 2020
Event	14th World Congress in Computational Mechanics - Paris, France Duration: 19 Jul 2020 → 24 Jul 2020

Conference

Conference	14th World Congress in Computational Mechanics
Country/Territory	France
City	Paris
Period	19/07/20 → 24/07/20

Keywords

computational fluid dynamics
haemodynamics
congential hearth diseases
pulmonary bifurcation

Access to Document

Boumpouli-etal-WCCM-2020-Patient-specific-blood-flow-simulations-in-the-pulmonaryAccepted author manuscript, 73.1 KB

Multi-scale computational hemodynamics in obese children and adolescents: enabling personalised prediction of cardiovascular disease (CALLIRHEO) H2020 MSCA IF
Gourlay, T. (Co-investigator) & Kazakidi, A. (Fellow)
European Commission - Horizon Europe + H2020
1/01/18 → 31/12/19
Project: Research Fellowship

Cite this

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title = "Patient-specific blood flow simulations in the pulmonary bifurcation of patients with tetralogy of fallot",

abstract = "Dysfunction of the pulmonary valve and narrowing of the branch pulmonary arteries are common chronic complications in adult patients with tetralogy of Fallot; the most common cyanotic congenital heart disease with an estimate prevalence 1 in 3000 live births. Clinical consequences include, but are not limited to, abnormal lung development and elevated pulmonary vascular resistance. It is, therefore, crucial to better understand and characterise the haemodynamic environment in the pulmonary bifurcation to better diagnose and treat these patients. In this study, we have focused on investigating the blood flow dynamics in patient-specific geometries of the pulmonary bifurcation by means of computational models. ",

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T1 - Patient-specific blood flow simulations in the pulmonary bifurcation of patients with tetralogy of fallot

AU - Boumpouli, M.

AU - Sauvage, E.

AU - Capelli, C.

AU - Schievano, S.

AU - Gourlay, T.

AU - Kazakidi, A.

PY - 2020/7/19

Y1 - 2020/7/19

N2 - Dysfunction of the pulmonary valve and narrowing of the branch pulmonary arteries are common chronic complications in adult patients with tetralogy of Fallot; the most common cyanotic congenital heart disease with an estimate prevalence 1 in 3000 live births. Clinical consequences include, but are not limited to, abnormal lung development and elevated pulmonary vascular resistance. It is, therefore, crucial to better understand and characterise the haemodynamic environment in the pulmonary bifurcation to better diagnose and treat these patients. In this study, we have focused on investigating the blood flow dynamics in patient-specific geometries of the pulmonary bifurcation by means of computational models.

AB - Dysfunction of the pulmonary valve and narrowing of the branch pulmonary arteries are common chronic complications in adult patients with tetralogy of Fallot; the most common cyanotic congenital heart disease with an estimate prevalence 1 in 3000 live births. Clinical consequences include, but are not limited to, abnormal lung development and elevated pulmonary vascular resistance. It is, therefore, crucial to better understand and characterise the haemodynamic environment in the pulmonary bifurcation to better diagnose and treat these patients. In this study, we have focused on investigating the blood flow dynamics in patient-specific geometries of the pulmonary bifurcation by means of computational models.

KW - computational fluid dynamics

KW - haemodynamics

KW - congential hearth diseases

KW - pulmonary bifurcation

M3 - Abstract

T2 - 14th World Congress in Computational Mechanics

Y2 - 19 July 2020 through 24 July 2020

ER -

Patient-specific blood flow simulations in the pulmonary bifurcation of patients with tetralogy of fallot

Abstract

Conference

Keywords

Access to Document

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Projects

Multi-scale computational hemodynamics in obese children and adolescents: enabling personalised prediction of cardiovascular disease (CALLIRHEO) H2020 MSCA IF

Cite this