Purpose/Objectives: To explore changes over time in self-efficacy and the predictive ability of changes in state anxiety and health-related quality of life during chemotherapy. Design: Secondary analysis of a longitudinal dataset derived from a larger, multicenter study. Setting: Outpatient oncology clinics across eight general hospitals in England, Scotland, and Northern Ireland. Sample: 137 patients scheduled to receive adjuvant chemotherapy for breast or colorectal cancer. Methods: At the beginning of each of six chemotherapy cycles, participants completed the Strategies Used by People to Promote Health questionnaire, the State-Trait Anxiety Inventory, and the Functional Assessment of Cancer Therapy-Breast or -Colorectal questionnaire. Multilevel model analysis was used to analyze longitudinal data, adjusted for demographic and clinical variables. Main research variables: Self-efficacy, anxiety, and health-related quality of life. Findings: No significant time effects were found for patients' overall perceived self-efficacy or self-efficacy parameters. A trend toward greater self-efficacy was evident as chemotherapy progressed. Self-efficacy was significantly associated with decreased state anxiety throughout chemotherapy. Increases in overall self-efficacy and perceived ability to maintain a positive attitude were significantly associated with over-time increases in physical, emotional, and functional well-being, as well as with fewer cancer-related concerns. Conclusions: Findings highlight the importance of clinical assessments throughout treatment that focus on patients' perceived self-efficacy as a positive regulator of mood and well-being. Implications for nursing: The current study suggests self-efficacy enhancement should be a key component of psycho-behavioral programs designed to support patients with cancer throughout chemotherapy.
- quality of life
Papadopoulou, C., Kotronoulas, G., Schneider, A., Miller, M. I., McBride, J., Polly, Z., Bettles, S., Whitehouse, A., McCann, L., Kearney, N., & Maguire, R. (2017). Patient-reported self-efficacy, anxiety, and health-related quality of life during chemotherapy: results from a longitudinal study. Oncology Nursing Forum, 44(1), 127-136. https://doi.org/10.1188/17.ONF.127-136