Paracetamol habit modification by impurities

Stephanie Urwin, Alan Martin, Joop Ter Horst

Research output: Contribution to conferencePoster

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Abstract

The presence of impurities during crystallisation can affect final crystal attributes other than chemical purity. For example,metacetamol, a regioisomer of paracetamol, has been reported to modify the morphology of the API, leading to theisolation of columnar crystals in place of crystals with an equant habit. Small scale recrystallisation of pure paracetamolfrom 2-propanol was found here to produce small, relatively equant crystals.
Original languageEnglish
Number of pages1
Publication statusPublished - 9 Jul 2019
Event50th Annual Conference of the British Association of Crystal Growth - London, United Kingdom
Duration: 9 Jul 201911 Jul 2019

Conference

Conference50th Annual Conference of the British Association of Crystal Growth
CountryUnited Kingdom
CityLondon
Period9/07/1911/07/19

Keywords

  • crystallisation impurities
  • chemical purity
  • recrystallisation
  • paracetomol

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