Palmitoylation and the trafficking of peripheral membrane proteins

Luke Chamberlain, Kimon Lemonidis, Maria Concepcion Sanchez Perez, Martin Werno, Oforiwa A. Gorleku, Jennifer Greaves

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.
Original languageEnglish
Pages (from-to)62-66
Number of pages5
JournalBiochemical Society Transactions
Issue number1
Publication statusPublished - 1 Feb 2013


  • palmitoylation
  • SNAP25
  • ras
  • s-acylation
  • DHHC proteins
  • cysteine-string protein
  • DHHC protein
  • 25 kDa synaptosomeassociated protein


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