Palmitoylation and the trafficking of peripheral membrane proteins

Luke Chamberlain, Kimon Lemonidis, Maria Concepcion Sanchez Perez, Martin Werno, Oforiwa A. Gorleku, Jennifer Greaves

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.
LanguageEnglish
Pages62-66
Number of pages5
JournalBiochemical Society Transactions
Volume41
Issue number1
DOIs
Publication statusPublished - 1 Feb 2013

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Lipoylation
Membrane Proteins
Palmitates
Post Translational Protein Processing
Cytosol
Cysteine
Fatty Acids
Fluxes
Membranes
Proteins

Keywords

  • palmitoylation
  • SNAP25
  • ras
  • s-acylation
  • DHHC proteins
  • cysteine-string protein
  • DHHC protein
  • 25 kDa synaptosomeassociated protein

Cite this

Chamberlain, L., Lemonidis, K., Sanchez Perez, M. C., Werno, M., Gorleku, O. A., & Greaves, J. (2013). Palmitoylation and the trafficking of peripheral membrane proteins. Biochemical Society Transactions, 41(1), 62-66. https://doi.org/10.1042/BST20120243
Chamberlain, Luke ; Lemonidis, Kimon ; Sanchez Perez, Maria Concepcion ; Werno, Martin ; Gorleku, Oforiwa A. ; Greaves, Jennifer. / Palmitoylation and the trafficking of peripheral membrane proteins. In: Biochemical Society Transactions. 2013 ; Vol. 41, No. 1. pp. 62-66.
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Chamberlain, L, Lemonidis, K, Sanchez Perez, MC, Werno, M, Gorleku, OA & Greaves, J 2013, 'Palmitoylation and the trafficking of peripheral membrane proteins' Biochemical Society Transactions, vol. 41, no. 1, pp. 62-66. https://doi.org/10.1042/BST20120243

Palmitoylation and the trafficking of peripheral membrane proteins. / Chamberlain, Luke; Lemonidis, Kimon; Sanchez Perez, Maria Concepcion; Werno, Martin; Gorleku, Oforiwa A.; Greaves, Jennifer.

In: Biochemical Society Transactions, Vol. 41, No. 1, 01.02.2013, p. 62-66.

Research output: Contribution to journalArticle

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