Palmitoylation and the trafficking of peripheral membrane proteins

Luke Chamberlain; Kimon Lemonidis; Maria Concepcion Sanchez Perez; Martin Werno; Oforiwa A.  Gorleku; Jennifer Greaves

doi:10.1042/BST20120243

Palmitoylation and the trafficking of peripheral membrane proteins

Luke Chamberlain, Kimon Lemonidis, Maria Concepcion Sanchez Perez, Martin Werno, Oforiwa A. Gorleku, Jennifer Greaves

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.

Original language	English
Pages (from-to)	62-66
Number of pages	5
Journal	Biochemical Society Transactions
Volume	41
Issue number	1
DOIs	https://doi.org/10.1042/BST20120243
Publication status	Published - 1 Feb 2013

Keywords

palmitoylation
SNAP25
ras
s-acylation
DHHC proteins
cysteine-string protein
DHHC protein
25 kDa synaptosomeassociated protein

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10.1042/BST20120243

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AU - Greaves, Jennifer

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Palmitoylation and the trafficking of peripheral membrane proteins

Abstract

Keywords

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