Palmitoylation and the trafficking of peripheral membrane proteins

Luke Chamberlain, Kimon Lemonidis, Maria Concepcion Sanchez Perez, Martin Werno, Oforiwa A. Gorleku, Jennifer Greaves

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.
Original languageEnglish
Pages (from-to)62-66
Number of pages5
JournalBiochemical Society Transactions
Volume41
Issue number1
DOIs
Publication statusPublished - 1 Feb 2013

Keywords

  • palmitoylation
  • SNAP25
  • ras
  • s-acylation
  • DHHC proteins
  • cysteine-string protein
  • DHHC protein
  • 25 kDa synaptosomeassociated protein

Fingerprint Dive into the research topics of 'Palmitoylation and the trafficking of peripheral membrane proteins'. Together they form a unique fingerprint.

  • Cite this

    Chamberlain, L., Lemonidis, K., Sanchez Perez, M. C., Werno, M., Gorleku, O. A., & Greaves, J. (2013). Palmitoylation and the trafficking of peripheral membrane proteins. Biochemical Society Transactions, 41(1), 62-66. https://doi.org/10.1042/BST20120243