Palladium‐catalyzed direct C-H functionalization of benzoquinone

Sarah E. Walker, James A. Jordan-Hore, David G. Johnson, Stuart A. Macgregor, Ai-Lan Lee

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

A direct Pd-catalyzed C-H functionalization of benzoquinone (BQ) can be controlled to give either mono- or disubstituted BQ, including the installation of two different groups in a one-pot procedure. BQ can now be directly functionalized with aryl, heteroaryl, cycloalkyl, and cycloalkene groups and, moreover, the reaction is conducted in environmentally benign water or acetone as solvents.
Original languageEnglish
Pages (from-to)13876-13879
Number of pages4
JournalAngewandte Chemie International Edition
Volume53
Issue number50
Early online date10 Oct 2014
DOIs
Publication statusPublished - 8 Dec 2014

Keywords

  • benzoquinone
  • C-H functionalization
  • palladium
  • synthetic methods
  • water

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