Palladium‐catalyzed direct C-H functionalization of benzoquinone

Sarah E. Walker, James A. Jordan-Hore, David G. Johnson, Stuart A. Macgregor, Ai-Lan Lee

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

A direct Pd-catalyzed C-H functionalization of benzoquinone (BQ) can be controlled to give either mono- or disubstituted BQ, including the installation of two different groups in a one-pot procedure. BQ can now be directly functionalized with aryl, heteroaryl, cycloalkyl, and cycloalkene groups and, moreover, the reaction is conducted in environmentally benign water or acetone as solvents.
Original languageEnglish
Pages (from-to)13876-13879
Number of pages4
JournalAngewandte Chemie International Edition
Volume53
Issue number50
Early online date10 Oct 2014
DOIs
Publication statusPublished - 8 Dec 2014

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Acetone
Cycloparaffins
Water
benzoquinone

Keywords

  • benzoquinone
  • C-H functionalization
  • palladium
  • synthetic methods
  • water

Cite this

Walker, Sarah E. ; Jordan-Hore, James A. ; Johnson, David G. ; Macgregor, Stuart A. ; Lee, Ai-Lan. / Palladium‐catalyzed direct C-H functionalization of benzoquinone. In: Angewandte Chemie International Edition. 2014 ; Vol. 53, No. 50. pp. 13876-13879.
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Walker, SE, Jordan-Hore, JA, Johnson, DG, Macgregor, SA & Lee, A-L 2014, 'Palladium‐catalyzed direct C-H functionalization of benzoquinone', Angewandte Chemie International Edition, vol. 53, no. 50, pp. 13876-13879. https://doi.org/10.1002/anie.201408054

Palladium‐catalyzed direct C-H functionalization of benzoquinone. / Walker, Sarah E.; Jordan-Hore, James A.; Johnson, David G.; Macgregor, Stuart A.; Lee, Ai-Lan.

In: Angewandte Chemie International Edition, Vol. 53, No. 50, 08.12.2014, p. 13876-13879.

Research output: Contribution to journalArticle

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