Palladium‐catalyzed direct C-H functionalization of benzoquinone

Sarah E. Walker; James A. Jordan-Hore; David G.  Johnson; Stuart A. Macgregor; Ai-Lan Lee

doi:10.1002/anie.201408054

Palladium‐catalyzed direct C-H functionalization of benzoquinone

Sarah E. Walker, James A. Jordan-Hore, David G. Johnson, Stuart A. Macgregor, Ai-Lan Lee

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

A direct Pd-catalyzed C-H functionalization of benzoquinone (BQ) can be controlled to give either mono- or disubstituted BQ, including the installation of two different groups in a one-pot procedure. BQ can now be directly functionalized with aryl, heteroaryl, cycloalkyl, and cycloalkene groups and, moreover, the reaction is conducted in environmentally benign water or acetone as solvents.

Original language	English
Pages (from-to)	13876-13879
Number of pages	4
Journal	Angewandte Chemie International Edition
Volume	53
Issue number	50
Early online date	10 Oct 2014
DOIs	https://doi.org/10.1002/anie.201408054
Publication status	Published - 8 Dec 2014

Keywords

benzoquinone
C-H functionalization
palladium
synthetic methods
water

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abstract = "A direct Pd-catalyzed C-H functionalization of benzoquinone (BQ) can be controlled to give either mono- or disubstituted BQ, including the installation of two different groups in a one-pot procedure. BQ can now be directly functionalized with aryl, heteroaryl, cycloalkyl, and cycloalkene groups and, moreover, the reaction is conducted in environmentally benign water or acetone as solvents.",

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AU - Lee, Ai-Lan

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KW - benzoquinone

KW - C-H functionalization

KW - palladium

KW - synthetic methods

KW - water

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DO - 10.1002/anie.201408054

M3 - Article

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Palladium‐catalyzed direct C-H functionalization of benzoquinone

Abstract

Keywords

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