A direct Pd-catalyzed C-H functionalization of benzoquinone (BQ) can be controlled to give either mono- or disubstituted BQ, including the installation of two different groups in a one-pot procedure. BQ can now be directly functionalized with aryl, heteroaryl, cycloalkyl, and cycloalkene groups and, moreover, the reaction is conducted in environmentally benign water or acetone as solvents.
|Number of pages||4|
|Journal||Angewandte Chemie International Edition|
|Early online date||10 Oct 2014|
|Publication status||Published - 8 Dec 2014|
- C-H functionalization
- synthetic methods