Pain intensity and quality of life perception in children with hypermobility syndrome

Francis Fatoye, Shea Palmer, Fiona Macmillan, Philip Rowe, Marietta van der Linden

    Research output: Contribution to journalArticle

    28 Citations (Scopus)


    Hypermobility syndrome (HMS) is a major source of morbidity in children. Impaired quality of life (QoL) has been observed recently in adults with HMS; however, this issue is yet to be investigated in children with this condition. This study compared pain intensity and QoL in children with HMS with healthy controls. It also examined the relationship between pain intensity and QoL in children with HMS. Following ethical approval, 29 children diagnosed with HMS and 37 healthy children aged 8-15 years participated. Informed written consent was obtained from participants and their parents/guardians. Average knee pain over the past week was examined using the Coloured Analogue Scale. QoL was measured via the Pediatric Quality of Life Inventory. Mann-Whitney U tests were performed to compare pain and QoL scores between the two groups. Spearman Rho correlation analysis was performed to examine the relationship between pain and QoL. Overall QoL scores in each domain were significantly lower in children with HMS (all p 
    Original languageEnglish
    Pages (from-to)1277-1284
    Number of pages8
    JournalRheumatology International
    Issue number5
    Publication statusPublished - 2012


    • hypermobility syndrome
    • pain
    • rheumatology

    Cite this