Overcoming drug resistance, the natural way

Matthew I. Hutchings, Katherine R. Duncan

Research output: Contribution to journalComment/debatepeer-review

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Colistin is an antibiotic of last resort for treating Gram-negative bacterial infections, but resistance is spreading rapidly. In a recent issue of Nature, Wang et al. use genome mining to identify and synthesize a natural variant that bypasses colistin resistance and offers new hope for tackling antimicrobial resistance.
Original languageEnglish
Pages (from-to)273-274
Number of pages2
JournalCell Host & Microbe
Issue number3
Publication statusPublished - 9 Mar 2022


  • anti-bacterial agents - pharmacology - therapeutic use
  • drug resistance
  • colistin - pharmacology - therapeutic use
  • humans
  • gram-negative bacterial Infections - drug therapy


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