Organocatalytic synthesis of highly substituted furfuryl alcohols and amines

Stephen Clark; Alistair Boyer; Anthony Aimon; Paloma Engel Garcia; David M. Lindsay; Andrew D F Symington; Yves Danoy

doi:10.1002/anie.201207300

Organocatalytic synthesis of highly substituted furfuryl alcohols and amines

Stephen Clark, Alistair Boyer, Anthony Aimon, Paloma Engel Garcia, David M. Lindsay, Andrew D F Symington, Yves Danoy

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

Tetrahydrothiophene is an efficient organocatalyst for the synthesis of highly substituted furfuryl products from readily accessible electron-poor enynes under neutral reaction conditions. This process is applicable to a wide range of nucleophiles and enynes and can be used in a domino organocatalysis sequence.

Original language	English
Pages (from-to)	12128-12131
Number of pages	4
Journal	Angewandte Chemie International Edition
Volume	51
Issue number	48
DOIs	https://doi.org/10.1002/anie.201207300
Publication status	Published - 24 Oct 2012

Keywords

domino reacitons
enynes
furans
organocatalysis
thioethers

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abstract = "Tetrahydrothiophene is an efficient organocatalyst for the synthesis of highly substituted furfuryl products from readily accessible electron-poor enynes under neutral reaction conditions. This process is applicable to a wide range of nucleophiles and enynes and can be used in a domino organocatalysis sequence.",

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AU - Clark, Stephen

AU - Boyer, Alistair

AU - Aimon, Anthony

AU - Garcia, Paloma Engel

AU - Lindsay, David M.

AU - Symington, Andrew D F

AU - Danoy, Yves

PY - 2012/10/24

Y1 - 2012/10/24

N2 - Tetrahydrothiophene is an efficient organocatalyst for the synthesis of highly substituted furfuryl products from readily accessible electron-poor enynes under neutral reaction conditions. This process is applicable to a wide range of nucleophiles and enynes and can be used in a domino organocatalysis sequence.

AB - Tetrahydrothiophene is an efficient organocatalyst for the synthesis of highly substituted furfuryl products from readily accessible electron-poor enynes under neutral reaction conditions. This process is applicable to a wide range of nucleophiles and enynes and can be used in a domino organocatalysis sequence.

KW - domino reacitons

KW - enynes

KW - furans

KW - organocatalysis

KW - thioethers

U2 - 10.1002/anie.201207300

DO - 10.1002/anie.201207300

M3 - Article

SN - 1433-7851

VL - 51

SP - 12128

EP - 12131

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

IS - 48

ER -

Organocatalytic synthesis of highly substituted furfuryl alcohols and amines

Abstract

Keywords

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