Organocatalytic synthesis of highly substituted furfuryl alcohols and amines

Stephen Clark, Alistair Boyer, Anthony Aimon, Paloma Engel Garcia, David M. Lindsay, Andrew D F Symington, Yves Danoy

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51 Citations (Scopus)

Abstract

Tetrahydrothiophene is an efficient organocatalyst for the synthesis of highly substituted furfuryl products from readily accessible electron-poor enynes under neutral reaction conditions. This process is applicable to a wide range of nucleophiles and enynes and can be used in a domino organocatalysis sequence.
Original languageEnglish
Pages (from-to)12128-12131
Number of pages4
JournalAngewandte Chemie International Edition
Volume51
Issue number48
DOIs
Publication statusPublished - 24 Oct 2012

Keywords

  • domino reacitons
  • enynes
  • furans
  • organocatalysis
  • thioethers

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    Clark, S., Boyer, A., Aimon, A., Garcia, P. E., Lindsay, D. M., Symington, A. D. F., & Danoy, Y. (2012). Organocatalytic synthesis of highly substituted furfuryl alcohols and amines. Angewandte Chemie International Edition , 51(48), 12128-12131. https://doi.org/10.1002/anie.201207300