Organocatalytic α-oxybenzoylation of aldehydes

Matti J. P. Vaismaa, Sze Chak Yau, Nicholas C. O. Tomkinson

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

A simple method for the asymmetric α-oxybenzoylation of aldehydes is presented. Treatment of a series of aldehydes with benzoyl peroxide in the presence of a MacMillan imidazolidinone leads directly to the α-oxybenzoylated product with excellent levels of asymmetric induction.
Original languageEnglish
Pages (from-to)3625-3627
Number of pages3
JournalTetrahedron Letters
Volume50
Issue number26
Early online date16 Mar 2009
DOIs
Publication statusPublished - 1 Jul 2009

Keywords

  • aldehydes
  • benzoyl peroxide
  • MacMillan imidazolidinone
  • asymmetric induction

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