Organocatalytic α-oxybenzoylation of aldehydes

Matti J. P. Vaismaa, Sze Chak Yau, Nicholas C. O. Tomkinson

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

A simple method for the asymmetric α-oxybenzoylation of aldehydes is presented. Treatment of a series of aldehydes with benzoyl peroxide in the presence of a MacMillan imidazolidinone leads directly to the α-oxybenzoylated product with excellent levels of asymmetric induction.
LanguageEnglish
Pages3625-3627
Number of pages3
JournalTetrahedron Letters
Volume50
Issue number26
Early online date16 Mar 2009
DOIs
Publication statusPublished - 1 Jul 2009

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Aldehydes
Benzoyl Peroxide

Keywords

  • aldehydes
  • benzoyl peroxide
  • MacMillan imidazolidinone
  • asymmetric induction

Cite this

Vaismaa, Matti J. P. ; Yau, Sze Chak ; Tomkinson, Nicholas C. O. / Organocatalytic α-oxybenzoylation of aldehydes. In: Tetrahedron Letters. 2009 ; Vol. 50, No. 26. pp. 3625-3627.
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Organocatalytic α-oxybenzoylation of aldehydes. / Vaismaa, Matti J. P.; Yau, Sze Chak; Tomkinson, Nicholas C. O.

In: Tetrahedron Letters, Vol. 50, No. 26, 01.07.2009, p. 3625-3627.

Research output: Contribution to journalArticle

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AU - Vaismaa, Matti J. P.

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AU - Tomkinson, Nicholas C. O.

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AB - A simple method for the asymmetric α-oxybenzoylation of aldehydes is presented. Treatment of a series of aldehydes with benzoyl peroxide in the presence of a MacMillan imidazolidinone leads directly to the α-oxybenzoylated product with excellent levels of asymmetric induction.

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KW - MacMillan imidazolidinone

KW - asymmetric induction

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