Organobase-catalyzed amidation of esters with amino alcohols

Nicola Caldwell; Craig Jamieson; Iain Simpson; Tell Tuttle

doi:10.1021/ol400987p

Organobase-catalyzed amidation of esters with amino alcohols

Nicola Caldwell, Craig Jamieson, Iain Simpson, Tell Tuttle

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

54 Citations (Scopus)

Abstract

A base-mediated procedure for the amidation of unactivated esters with amino alcohols is reported. Optimization and exemplification of the catalytic process are described, furnishing products in 40-100% isolated yield.

Original language	English
Pages (from-to)	2506-2509
Number of pages	4
Journal	Organic Letters
Volume	15
Issue number	10
Early online date	2 May 2013
DOIs	https://doi.org/10.1021/ol400987p
Publication status	Published - 17 May 2013

Keywords

reagents
convenient
catalytic process
unactivated esters
efficient
carboxylic acids

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10.1021/ol400987p

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title = "Organobase-catalyzed amidation of esters with amino alcohols",

abstract = "A base-mediated procedure for the amidation of unactivated esters with amino alcohols is reported. Optimization and exemplification of the catalytic process are described, furnishing products in 40-100% isolated yield.",

keywords = "reagents, convenient, catalytic process, unactivated esters, efficient, carboxylic acids ",

author = "Nicola Caldwell and Craig Jamieson and Iain Simpson and Tell Tuttle",

year = "2013",

month = may,

day = "17",

doi = "10.1021/ol400987p",

language = "English",

volume = "15",

pages = "2506--2509",

journal = "Organic Letters",

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number = "10",

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T1 - Organobase-catalyzed amidation of esters with amino alcohols

AU - Caldwell, Nicola

AU - Jamieson, Craig

AU - Simpson, Iain

AU - Tuttle, Tell

PY - 2013/5/17

Y1 - 2013/5/17

N2 - A base-mediated procedure for the amidation of unactivated esters with amino alcohols is reported. Optimization and exemplification of the catalytic process are described, furnishing products in 40-100% isolated yield.

AB - A base-mediated procedure for the amidation of unactivated esters with amino alcohols is reported. Optimization and exemplification of the catalytic process are described, furnishing products in 40-100% isolated yield.

KW - reagents

KW - convenient

KW - catalytic process

KW - unactivated esters

KW - efficient

KW - carboxylic acids

UR - http://pubs.acs.org/journal/orlef7

U2 - 10.1021/ol400987p

DO - 10.1021/ol400987p

M3 - Article

SN - 1523-7060

VL - 15

SP - 2506

EP - 2509

JO - Organic Letters

JF - Organic Letters

IS - 10

ER -

Organobase-catalyzed amidation of esters with amino alcohols

Abstract

Keywords

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