Organobase-catalyzed amidation of esters with amino alcohols

Nicola Caldwell, Craig Jamieson, Iain Simpson, Tell Tuttle

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)


A base-mediated procedure for the amidation of unactivated esters with amino alcohols is reported. Optimization and exemplification of the catalytic process are described, furnishing products in 40-100% isolated yield.

Original languageEnglish
Pages (from-to)2506-2509
Number of pages4
JournalOrganic Letters
Issue number10
Early online date2 May 2013
Publication statusPublished - 17 May 2013


  • reagents
  • convenient
  • catalytic process
  • unactivated esters
  • efficient
  • carboxylic acids

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