Organic semiconductor laser biosensor: design and performance discussion

Organic distributed feedback lasers can detect nanoscale materials and are therefore an attractive sens- ing platform for biological and medical applications. In this paper, we present a model for optimizing such laser sensors and discuss the advantages of using an organic semiconductor as the laser material in comparison to dyes in a matrix. The structure of the sensor and its operation principle are described. Bulk and surface sensing exper- imental data using oligofluorene truxene macromolecules and a conjugated polymer for the gain region is shown to correspond to modeled values and is used to assess the biosensing attributes of the sensor. A comparison between organic semiconductor and dye-doped laser sensitivity is made and analyzed theoretically. Finally, experimental and theoretical specific biosensing data is provided and methods for improving sensitivity are discussed.