Ophthalmic drug delivery systems for the treatment of retinal diseases: Basic research to clinical applications

Henry F. Edelhauser,, Cheryl L. Rowe-Rendleman, Michael R. Robinson, Daniel G. Dawson, Gerald J. Chader, Hans E. Grossniklaus, Kay D. Rittenhouse, Clive G. Wilson, David A. Weber

Research output: Contribution to journalArticle

138 Citations (Scopus)

Abstract

The basic science part of this article focuses on the anatomic barriers to the five major modes of ocular drug delivery: intraocular, periocular, hybrid, topical, and systemic. The second half is a review of the clinical and regulatory components of translational science.

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Retinal Diseases
Drug Delivery Systems
Research
Therapeutics
Pharmaceutical Preparations

Keywords

  • ocular
  • drug delivery
  • intraocular
  • periocular
  • hybrid
  • topical
  • systemic
  • translational science

Cite this

Henry F. Edelhauser,, Rowe-Rendleman, C. L., Robinson, M. R., Dawson, D. G., Chader, G. J., Grossniklaus, H. E., ... Weber, D. A. (2010). Ophthalmic drug delivery systems for the treatment of retinal diseases: Basic research to clinical applications. Investigative Ophthalmology and Visual Science, 51(11), 5403-5420. https://doi.org/10.1167/iovs.10-5392
Henry F. Edelhauser, ; Rowe-Rendleman, Cheryl L. ; Robinson, Michael R. ; Dawson, Daniel G. ; Chader, Gerald J. ; Grossniklaus, Hans E. ; Rittenhouse, Kay D. ; Weber, David A. . / Ophthalmic drug delivery systems for the treatment of retinal diseases : Basic research to clinical applications. In: Investigative Ophthalmology and Visual Science. 2010 ; Vol. 51, No. 11. pp. 5403-5420.
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Henry F. Edelhauser, Rowe-Rendleman, CL, Robinson, MR, Dawson, DG, Chader, GJ, Grossniklaus, HE, Rittenhouse, KD & Weber, DA 2010, 'Ophthalmic drug delivery systems for the treatment of retinal diseases: Basic research to clinical applications' Investigative Ophthalmology and Visual Science, vol. 51, no. 11, pp. 5403-5420. https://doi.org/10.1167/iovs.10-5392

Ophthalmic drug delivery systems for the treatment of retinal diseases : Basic research to clinical applications. / Henry F. Edelhauser,; Rowe-Rendleman, Cheryl L. ; Robinson, Michael R. ; Dawson, Daniel G. ; Chader, Gerald J. ; Grossniklaus, Hans E. ; Rittenhouse, Kay D. ; Weber, David A. .

In: Investigative Ophthalmology and Visual Science, Vol. 51, No. 11, 01.11.2010, p. 5403-5420.

Research output: Contribution to journalArticle

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AU - Robinson, Michael R.

AU - Dawson, Daniel G.

AU - Chader, Gerald J.

AU - Grossniklaus, Hans E.

AU - Rittenhouse, Kay D.

AU - Wilson, Clive G.

AU - Weber, David A.

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KW - topical

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Henry F. Edelhauser, Rowe-Rendleman CL, Robinson MR, Dawson DG, Chader GJ, Grossniklaus HE et al. Ophthalmic drug delivery systems for the treatment of retinal diseases: Basic research to clinical applications. Investigative Ophthalmology and Visual Science. 2010 Nov 1;51(11):5403-5420. https://doi.org/10.1167/iovs.10-5392