Oomycete RXLR effectors: delivery, functional redundancy and durable disease resistance

Paul RJ Birch, Petra C. Boevink, Eleanor M. Gilroy, Ingo Hein, Leighton Pritchard, Stephen C. Whisson

Research output: Contribution to journalReview articlepeer-review

119 Citations (Scopus)


To manipulate host defences, plant pathogenic oomycetes secrete and translocate RXLR effectors into plant cells. Recent reports have indicated that RXLR effectors are translocated from the extrahaustorial matrix during the biotrophic phase of infection and that they are able to suppress PAMP-triggered immunity. Oomycete genomes contain potentially hundreds of highly diverse RXLR effector genes, providing the potential for considerable functional redundancy and the consequent ability to readily shed effectors that are recognised by plant surveillance systems without compromising pathogenic fitness. Understanding how these effectors are translocated, their precise roles in virulence, and the extent to which functional redundancy exists in oomycete RXLR effector complements, are major challenges for the coming years.

Original languageEnglish
Pages (from-to)373-379
Number of pages7
JournalCurrent Opinion in Plant Biology
Issue number4
Early online date27 May 2008
Publication statusPublished - 1 Aug 2008


  • pathogens
  • RXLR effectors
  • plant pathogens
  • oomycete effector proteins


Dive into the research topics of 'Oomycete RXLR effectors: delivery, functional redundancy and durable disease resistance'. Together they form a unique fingerprint.

Cite this