Abstract
Release of acetylcholine at the neuromuscular junctions of skeletal muscle is not sensitive to organic Ca2+ channel blockers. However, in mouse motor nerve endings, extracellular recording reveals that a verapamil-sensitive Ca2+ current can be induced after block of K+ channels. Recordings of extracellular action potentials from inside the perineural sheaths of nerves innervating mouse triangularis sterni muscles reveal that this verapamil-sensitive current is not blocked by omega-conotoxin, and hence, it does not involve channels similar to the L-channels of neuronal cell bodies.
Original language | English |
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Pages (from-to) | 177-180 |
Number of pages | 4 |
Journal | Neuroscience Letters |
Volume | 82 |
Issue number | 2 |
DOIs | |
Publication status | Published - 23 Nov 1987 |
Keywords
- animals
- anura
- calcium
- ion channels
- male
- mice
- inbred BALB C mice
- mollusk venoms
- nerve block
- neuromuscular junction
- verapamil
- omega-conotoxins