Ocular toxoplasmosis occurs during the acute acquired infection, during active congenital infection in utero and the newborn period and as a recudescent sequela of both types of infection. It also occurs in immune compromised persons usually as reactivation disease. Destruction of the eye is secondary to parasite replication and the immune response to parasite growth may augment this destruction. Clinical features, parthogenesis, immunology and protective and pathogenic mechanisms, pathology, animal models for study of the disease, and methods of treatment are summerized and discussed.
|Title of host publication||Toxoplasma|
|Subtitle of host publication||Molecular and Cellular Biology|
|Editors||James W. Ajioka, Dominique Soldati|
|Place of Publication||Norfolk|
|Number of pages||33|
|Publication status||Published - 31 Jul 2007|
- Toxoplasma gondii
- ocular toxoplasmosis
Roberts, F., Kuo, A., Jones, L., McLeod, R., & Roberts, C. (2007). Ocular toxoplasmosis: clinical features, pathology, pathogenesis, animal models and immune responses . In J. W. Ajioka, & D. Soldati (Eds.), Toxoplasma: Molecular and Cellular Biology (pp. 59-91).