Ocular toxoplasmosis: clinical features, pathology, pathogenesis, animal models and immune responses 

Fiona Roberts, Annie Kuo, Leigh Jones, Rima McLeod, Craig Roberts

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Ocular toxoplasmosis occurs during the acute acquired infection, during active congenital infection in utero and the newborn period and as a recudescent sequela of both types of infection. It also occurs in immune compromised persons usually as reactivation disease. Destruction of the eye is secondary to parasite replication and the immune response to parasite growth may augment this destruction. Clinical features, parthogenesis, immunology and protective and pathogenic mechanisms, pathology, animal models for study of the disease, and methods of treatment are summerized and discussed.
Original languageEnglish
Title of host publicationToxoplasma
Subtitle of host publicationMolecular and Cellular Biology
EditorsJames W. Ajioka, Dominique Soldati
Place of PublicationNorfolk
Pages59-91
Number of pages33
Publication statusPublished - 31 Jul 2007

Keywords

  • Toxoplasma gondii
  • ocular toxoplasmosis
  • parasite

Cite this

Roberts, F., Kuo, A., Jones, L., McLeod, R., & Roberts, C. (2007). Ocular toxoplasmosis: clinical features, pathology, pathogenesis, animal models and immune responses . In J. W. Ajioka, & D. Soldati (Eds.), Toxoplasma: Molecular and Cellular Biology (pp. 59-91).