Objectively measured physical activity and fat mass in a large cohort of children

AR Ness, S.D. Leary, C. Mattocks, S.N. Blair, John J Reilly, JCK Wells, K. Ingleby, K. Tilling, G. Davey-Smith, C. Riddoch

Research output: Contribution to journalArticle

288 Citations (Scopus)

Abstract

Previous studies have been unable to characterise the association between physical activity and obesity, possibly because most relied on inaccurate measures of physical activity and obesity. We carried out a cross sectional analysis on 5,500 12-year-old children enrolled in the Avon Longitudinal Study of Parents and Children. Total physical activity and minutes of moderate and vigorous physical activity (MVPA) were measured using the Actigraph accelerometer. Fat mass and obesity (defined as the top decile of fat mass) were measured using the Lunar Prodigy dual x-ray emission absorptiometry scanner. We found strong negative associations between MVPA and fat mass that were unaltered after adjustment for total physical activity. We found a strong negative dose-response association between MVPA and obesity. The odds ratio for obesity in adjusted models between top and the bottom quintiles of minutes of MVPA was 0.03 (95% confidence interval [CI] 0.01-0.13, p-value for trend <0.0001) in boys and 0.36 (95% CI 0.17-0.74, p-value for trend = 0.006) in girls. We demonstrated a strong graded inverse association between physical activity and obesity that was stronger in boys. Our data suggest that higher intensity physical activity may be more important than total activity.
LanguageEnglish
Article numbere97
Number of pages9
JournalPLOS Medicine
Volume4
Issue number3
DOIs
Publication statusPublished - 20 Mar 2007

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Fats
Exercise
Obesity
Confidence Intervals
Longitudinal Studies
Cross-Sectional Studies
Parents
Odds Ratio
X-Rays

Keywords

  • physical activity
  • obesity
  • Actigraph accelerometer
  • fat mass
  • intensity

Cite this

Ness, AR., Leary, S. D., Mattocks, C., Blair, S. N., Reilly, J. J., Wells, JCK., ... Riddoch, C. (2007). Objectively measured physical activity and fat mass in a large cohort of children. PLOS Medicine, 4(3), [e97]. https://doi.org/10.1371/journal.pmed.0040097
Ness, AR ; Leary, S.D. ; Mattocks, C. ; Blair, S.N. ; Reilly, John J ; Wells, JCK ; Ingleby, K. ; Tilling, K. ; Davey-Smith, G. ; Riddoch, C. / Objectively measured physical activity and fat mass in a large cohort of children. In: PLOS Medicine. 2007 ; Vol. 4, No. 3.
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Ness, AR, Leary, SD, Mattocks, C, Blair, SN, Reilly, JJ, Wells, JCK, Ingleby, K, Tilling, K, Davey-Smith, G & Riddoch, C 2007, 'Objectively measured physical activity and fat mass in a large cohort of children' PLOS Medicine, vol. 4, no. 3, e97. https://doi.org/10.1371/journal.pmed.0040097

Objectively measured physical activity and fat mass in a large cohort of children. / Ness, AR; Leary, S.D.; Mattocks, C.; Blair, S.N.; Reilly, John J; Wells, JCK; Ingleby, K.; Tilling, K.; Davey-Smith, G.; Riddoch, C.

In: PLOS Medicine, Vol. 4, No. 3, e97, 20.03.2007.

Research output: Contribution to journalArticle

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AU - Ness, AR

AU - Leary, S.D.

AU - Mattocks, C.

AU - Blair, S.N.

AU - Reilly, John J

AU - Wells, JCK

AU - Ingleby, K.

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AU - Davey-Smith, G.

AU - Riddoch, C.

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