Visible light irradiation of inert [PtIV(diam(m)ine)(diazide)] complexes leads to reductive elimination of the azide ligands, production of N2, and formation of bifunctional adducts with guanine bases of the type which are lethal to cancer cells.
- novel platinum (IV) azide complexes
- cancer cells
Parkinson, J. A., Muller, P., Shroder, B., Kratochwil, N. A., Coxall, R. A., Parkin, A., ... Sadler, P. J. (2003). Nucleotide cross-linking induced by photoreactions of novel platinum (IV) azide complexes. Angewandte Chemie, 42(3), 335-339. https://doi.org/10.1002/anie.200390110