Abstract
| Language | English |
|---|---|
| Pages | 335-339 |
| Number of pages | 5 |
| Journal | Angewandte Chemie |
| Volume | 42 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2003 |
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Keywords
- photoreactions
- novel platinum (IV) azide complexes
- cancer cells
- irradiation
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Nucleotide cross-linking induced by photoreactions of novel platinum (IV) azide complexes. / Parkinson, J.A.; Muller, P.; Shroder, B.; Kratochwil, N.A.; Coxall, R.A.; Parkin, A.; Parsons, S.; Sadler, P.J.
In: Angewandte Chemie, Vol. 42, No. 3, 2003, p. 335-339.Research output: Contribution to journal › Article
TY - JOUR
T1 - Nucleotide cross-linking induced by photoreactions of novel platinum (IV) azide complexes
AU - Parkinson, J.A.
AU - Muller, P.
AU - Shroder, B.
AU - Kratochwil, N.A.
AU - Coxall, R.A.
AU - Parkin, A.
AU - Parsons, S.
AU - Sadler, P.J.
PY - 2003
Y1 - 2003
N2 - Visible light irradiation of inert [PtIV(diam(m)ine)(diazide)] complexes leads to reductive elimination of the azide ligands, production of N2, and formation of bifunctional adducts with guanine bases of the type which are lethal to cancer cells.
AB - Visible light irradiation of inert [PtIV(diam(m)ine)(diazide)] complexes leads to reductive elimination of the azide ligands, production of N2, and formation of bifunctional adducts with guanine bases of the type which are lethal to cancer cells.
KW - photoreactions
KW - novel platinum (IV) azide complexes
KW - cancer cells
KW - irradiation
U2 - 10.1002/anie.200390110
DO - 10.1002/anie.200390110
M3 - Article
VL - 42
SP - 335
EP - 339
JO - Angewandte Chemie International Edition
T2 - Angewandte Chemie International Edition
JF - Angewandte Chemie International Edition
SN - 1433-7851
IS - 3
ER -