Non-lateralised deficits in anti-saccade performance in patients with hemispatial neglect

S.H. Butler, Stephanie Rossit, I.D. Gilchrist, C.J.H. Ludwig, Bettina Olk, Keith Muir, Ian Reeves, Monika Harvey

Research output: Contribution to journalArticle

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Abstract

We tested patients suffering from hemispatial neglect on the anti-saccade paradigm to assess voluntary control of saccades. In this task participants are required to saccade away from an abrupt onset target. As has been previously reported, in the pro-saccade condition neglect patients showed increased latencies towards targets presented on the left and their accuracywas reduced as a result of greater undershoot. To our surprise though, in the anti-saccade condition, we found strong bilateral effects: the neglect patients produced large numbers of erroneous pro-saccades to both left and right stimuli. This deficit in voluntary control was present even in patients whose lesions spared the frontal lobes. These results suggest that the voluntary control of action is supported by an integrated network of cortical regions, including more posterior areas. Damage to one or more components within this networkmay result in impaired voluntary control.
LanguageEnglish
Pages2488-2495
Number of pages8
JournalNeuropsychologia
Volume47
Issue number12
DOIs
Publication statusPublished - Oct 2009

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Perceptual Disorders
Saccades
Frontal Lobe

Keywords

  • stroke
  • pro-saccades
  • voluntary control
  • oculomotor control
  • inhibition
  • hemispatial neglect
  • non-lateralised deficits
  • anti-saccade performance
  • patients

Cite this

Butler, S. H., Rossit, S., Gilchrist, I. D., Ludwig, C. J. H., Olk, B., Muir, K., ... Harvey, M. (2009). Non-lateralised deficits in anti-saccade performance in patients with hemispatial neglect. Neuropsychologia, 47(12), 2488-2495. https://doi.org/10.1016/j.neuropsychologia.2009.04.022
Butler, S.H. ; Rossit, Stephanie ; Gilchrist, I.D. ; Ludwig, C.J.H. ; Olk, Bettina ; Muir, Keith ; Reeves, Ian ; Harvey, Monika. / Non-lateralised deficits in anti-saccade performance in patients with hemispatial neglect. In: Neuropsychologia. 2009 ; Vol. 47, No. 12. pp. 2488-2495.
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Butler, SH, Rossit, S, Gilchrist, ID, Ludwig, CJH, Olk, B, Muir, K, Reeves, I & Harvey, M 2009, 'Non-lateralised deficits in anti-saccade performance in patients with hemispatial neglect' Neuropsychologia, vol. 47, no. 12, pp. 2488-2495. https://doi.org/10.1016/j.neuropsychologia.2009.04.022

Non-lateralised deficits in anti-saccade performance in patients with hemispatial neglect. / Butler, S.H.; Rossit, Stephanie; Gilchrist, I.D.; Ludwig, C.J.H.; Olk, Bettina; Muir, Keith; Reeves, Ian; Harvey, Monika.

In: Neuropsychologia, Vol. 47, No. 12, 10.2009, p. 2488-2495.

Research output: Contribution to journalArticle

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AU - Harvey, Monika

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